345291-01-2

Basic information

• Product Name: (2-Hydroxy-2-phenyl-1-pyrrol-1-yl-ethyl)-phosphonic acid diethyl ester
• CAS NO: 345291-01-2
• Molecular Weight: 323.329
• Mol File: 345291-01-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2-Hydroxy-2-phenyl-1-pyrrol-1-yl-ethyl)-phosphonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2-Hydroxy-2-phenyl-1-pyrrol-1-yl-ethyl)-phosphonic acid diethyl ester(345291-01-2)
• EPA Substance Registry System: (2-Hydroxy-2-phenyl-1-pyrrol-1-yl-ethyl)-phosphonic acid diethyl ester(345291-01-2)

Safety Data

• Hazardous Substances Data: 345291-01-2(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 51297-15-5 α-Pyrrolomethanphosphonsaeurediethylester 
• 70908-61-1 diethyl N-(benzyloxycarbonyl) amidomethyl phosphonate 
• 41003-95-6 N-Formylaminomethanphosphonsaeurediethylester 

Downstream Products

• 81374-48-3 1-[(E)-2-phenylethenyl]-1H-pyrrole 

Relevant articles and documents

α-Substituted Phosphonates. 37. Derivatives of α-Pyrrolomethanephosphonic Acid and N-Vinylpyrroles

Diethyl α-aminomethanephosphonate 5a and its α-aryl derivatives 5b-d react with 2,5-diethoxytetrahydrofuran 1 to give diethyl α-pyrrolomethanephosphonate 9a and the α-aryl derivatives 9b-d, respectively.The pyrrolo derivatives 9 can be converted into the lithium salts 15 and 16, respectively, which with carbonyl compounds undergo the Horner reaction yielding E/Z mixtures of N-vinylpyrroles 18.In certain cases the intermediate of the Horner reaction, the β-hydroxyphosphonate, 17 can be isolated.The pyrrolo-analogue of stilbene, 18a, is formed only as E-isomer.On treating the lithium salts 15 and 16 with 9 or with alkyl halides α-C-alkylated pyrrolophosphonates 22 and 23, respectively, are obtained.