34591-21-4

Basic information

• Product Name: Phenol, 4-(3-phenylpropyl)-
• CAS NO: 34591-21-4
• Molecular Formula: C15H16O
• Molecular Weight: 212.291
• Mol File: 34591-21-4.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(3-phenylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(3-phenylpropyl)-(34591-21-4)
• EPA Substance Registry System: Phenol, 4-(3-phenylpropyl)-(34591-21-4)

Safety Data

• Hazardous Substances Data: 34591-21-4(Hazardous Substances Data)

Upstream product

• 20426-12-4 (E)-3-(4-hydroxyphenyl)-1-phenyl-2-propen-1-one 
• 38239-55-3 4-hydroxychalcone 
• 98-86-2 acetophenone 
• 123-08-0 4-hydroxy-benzaldehyde 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 61078-39-5 1-Benzyloxy-4-((1S,2R)-2-phenyl-cyclopropyl)-benzene 
• 126582-25-0 1,1-dichloro-cis-2-(4-benzyloxyphenyl)-3-phenylcyclopropane 
• 21148-30-1 3-(4-hydroxyphenyl)-1-phenylprop-1-ene 
• 2657-25-2 4'-hydroxychalcone 

Downstream Products

• 113795-29-2 1-(3-Bromo-propoxy)-4-(3-phenyl-propyl)-benzene 
• 113795-05-4 2,2-Dimethyl-5-[4-(3-phenyl-propyl)-phenoxy]-pentanoic acid 
• 61270-17-5 1-[2-hydroxy-5-(3-phenyl-propyl)-phenyl]-ethanone 
• 170012-73-4 1-acetoxy-4-(3-phenyl-propyl)-benzene 

Relevant articles and documents

Thermolysis of Surface-Attached 1,3-Diphenylpropane: Radical Chain Induced Decomposition under Conditions of Restricted Diffusion

Surface-immobilized 1,3-diphenylpropane (Ph(CH2)3Ph, or DPP) has been prepared by the condensation of p-(3-phenylpropyl)phenol with the surface hydroxyl groups of an amorphous, fumed silica.Thermolysis studies of the covalently attached DPP have

Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues

(Chemical Equqation Presented). A series of readily synthesized and inexpensive aminoalkylated chalcones and diarylpropane analogues (1-55) were synthesized and tested against chloroquinone-sensitive (D10 and NF54) and -resistant (Dd2 and K1) strains of Plasmodium falciparum. Hydrogenation of the enone to a diarylpropane moiety increased antiplasmodial bioactivity significantly. The influence of the structure of the amine moiety, A-ring substituents, propyl vs ethyl linker, and chloride salt formation on further enhancing antiplasmodial activity was investigated. Several compounds have IC50 values similar to or better than chloroquine (CQ). The most active compound (26) had an IC50 value of 0.01 μM. No signs of resistance were detected, as can be expected from compounds with structures unrelated to CQ and other currently used antimalarial drugs. Toxicity tests (in vitro CHO cell assay) gave high SI indices.

Antagonists of slow reacting substance of anaphylaxis. Synthesis of a series of chromone-2-carboxylic acids.

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