34642-42-7

Basic information

• Product Name: trifluoromethanesulfinic acid
• Synonyms: methanesulfinic acid, 1,1,1-trifluoro-
• CAS NO: 34642-42-7
• Molecular Formula: CHF₃O₂S
• Molecular Weight: 134.0776
• Mol File: 34642-42-7.mol

Chemical Properties

• Boiling Point: 222.8°C at 760 mmHg
• Flash Point: 88.5°C
• Density: 1.958g/cm³
• Vapor Pressure: 0.0369mmHg at 25°C
• Refractive Index: 1.425
• CAS DataBase Reference: trifluoromethanesulfinic acid(CAS DataBase Reference)
• NIST Chemistry Reference: trifluoromethanesulfinic acid(34642-42-7)
• EPA Substance Registry System: trifluoromethanesulfinic acid(34642-42-7)

Safety Data

• Hazardous Substances Data: 34642-42-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Production:
Trifluoromethanesulfinic acid is used as a reagent in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicines. Its strong oxidizing capabilities play a crucial role in the formation of complex molecular structures required for effective drug compounds.
Used in Agricultural Chemical Production:
In the agricultural sector, trifluoromethanesulfinic acid is employed as a reagent for the synthesis of agricultural chemicals, such as pesticides and herbicides. Its oxidizing properties facilitate the creation of compounds that can effectively control pests and weeds, thereby enhancing crop protection.
Used in Specialty Chemical Production:
Trifluoromethanesulfinic acid is utilized in the production of specialty chemicals, which are tailored for specific applications in various industries. Its versatility as a reagent allows for the creation of unique chemical products that meet the demands of specialized markets.
Used in Industrial Processes:
trifluoromethanesulfinic acid is also used in certain industrial processes, where its strong acidic and oxidizing properties are harnessed to drive chemical reactions and improve manufacturing efficiency.
Used in Research Laboratories:
Trifluoromethanesulfinic acid is employed in research settings for a variety of applications, including the study of chemical reactions, the development of new synthetic methods, and the exploration of potential uses in various fields. Its reactivity and oxidizing nature make it a valuable tool for scientific investigation.

Upstream product

• 64-17-5 ethanol 
• 35896-45-8 Benzyl Trifluoromethanesulfinate 
• 130774-56-0 p-Methylbenzyl Trifluoromethanesulfinate 
• 130774-55-9 p-Chlorobenzyl Trifluoromethanesulfinate 
• 75-63-8 Bromotrifluoromethane 
• 106-45-6 para-thiocresol 
• 421-17-0 Trifluoromethylsulfenyl chloride 
• 421-83-0 trifluoromethane sulfonyl chloride 
• 123-54-6 acetylacetone 
• 105-53-3 diethyl malonate 
• 335-05-7 Trifluoromethanesulfonyl fluoride 
• 2923-16-2 potassium trifluoroacetate 
• 41804-89-1 potassium triflinate 
• 2712-93-8 dichlorofluoromethanesulphenyl chloride 

Downstream Products

• 51735-75-2 trimethylsilyl trifluoromethanesulfonate 
• 2926-29-6 Langlois reagent 
• 75-46-7 trifluoromethan 
• 51735-76-3 CF₃S(O)OSn(CH₃)3 
• 30957-43-8 Trifluormethylsulfinsaeureethylester 
• 120068-37-3 fipronil 
• 41804-89-1 potassium triflinate 

Relevant articles and documents

Fluoroalkylation of thiophenols with Freons using conjugated electron transfer mediator systems composed of methylviologen-SO2 and I2-SO2

Methylviologen-sulfur dioxide and iodine (iodide)-sulfur dioxide have been shown to mediate electron transfer from thiophenols to Freons and perform the fluoroalkylation of thiophenols under mild conditions.

METHOD FOR PREPARING A SULFONIMIDE COMPOUND AND SALTS THEREOF

The present invention relates to a method for preparing an aqueous sulfonimide compound of the formula (Rf1—SO2) (Rf2—SO2)NH, wherein Rf1et Rf2 are independently selected from the group comprising: a fluorine atom and groups having 1 to 10 carbon atoms selected from the perfluoroalkyl, fluoroalkyl, fluoroalkenyl and fluoroallyl groups, from a mixture M1 including (Rf1—SO2)(Rf2—SO2)NH, Rf1SO2H and/or Rf2SO2H, Rf1SO2NH2 and/or Rf2SO2NH2, characterized in that said method includes an oxidation step of said mixture M1 using an oxidizing agent in order to obtain a mixture M2 including (Rf1—SO2)(Rf2—SO2)NH, Rf1SO3H and/or Rf2SO3H, and Rf1SO2NH2 and/or Rf2SO2NH2.

METHOD FOR PREPARING TRIFLUOROMETHANESULPHINIC ACID

The present invention relates to a method for preparing a highly pure trifluoromethanesulphinic acid. The method of the invention for preparing a highly pure trifluoromethanesulphinic acid, starting from an aqueous mixture comprising a trifluoromethanesulphinic acid salt, a trifluoroacetic acid salt and saline impurities resulting from the method for preparing same, is characterized in that said mixture is subjected to the following operations:- acidification such that the trifluoroacetic acid salt and the triflinic acid salt are released in an acid form,- separation of the trifluoroacetic acid and trifluoromethanesulphinic acid by distillation enabling the trifluoroacetic acid to be recovered at the top of the distillation and the trifluoromethanesulphinic acid to be recovered at the bottom of the distillation,- separation by distillation of the trifluoromethanesulphinic acid present in the distillation residue previously obtained.

THE SYNTHESIS, SOLVOLYSIS AND REARRANGEMENT OF BENZYL TRIFLUOROMETHANESULFINATES

The synthesis and reactivity of benzyl trifluoromethanesulfinates have been investigated.These esters are easily and almost quantitatively obtained by selective oxidation of the corresponding sulfenates.A study of their behavior has revealed some unique features.In sharp contrast to benzyl arenesulfinates, which undergo ethanolysis with complete sulfur-oxygen bond fission, the corresponding trifluoromethanesulfinates undergo ethanolysis with exclusive carbon-oxygen bond fission, and with a rate enhancement by a factor of 6 powers of ten.The unusual high reactivity of these esters, comparable to that of the corresponding tosylates, is discussed.A kinetic study of the solvent and substituents effects on the rate of solvolysis has been performed.Also in contrast with benzyl arenesulfinates, these esters undergo facile rearrangement to sulfone on heating in polar nonhydroxylic solvents such as acetonitrile, in high yields.The mechanisms of solvolysis and rearrangement are discussed.