trifluoromethanesulfinic acid

Base Information

• Chemical Name: trifluoromethanesulfinic acid
• CAS No.: 34642-42-7
• Molecular Formula: CHF3O2S
• Molecular Weight: 134.079
• Mol file: 34642-42-7.mol

Synonyms:trifluoromethanesulfinic acid;Trifluor-methansulfinsaeure;trifluoromethylsulfinic acid;trifluoromethanesulfonic acid;trifluoro-methanesulfinic acid;

Chemical Property of trifluoromethanesulfinic acid

Chemical Property:

• Vapor Pressure: 0.0369mmHg at 25°C
• Boiling Point: 222.8°C at 760 mmHg
• Flash Point: 88.5°C
• PSA: 56.51000
• Density: 1.958g/cm³
• LogP: 1.59360

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trifluoromethanesulfinic acid

There total 16 articles about trifluoromethanesulfinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

trifluoromethane sulfonyl chloride (421-83-0) + diethyl malonate (105-53-3) → diethyl dichloromalonate (20165-81-5) + trifluoromethanesulfinic acid (34642-42-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 10 - 50 ℃; Reagent/catalyst; Solvent; Mechanism;

DOI:10.1134/S1070428009090176

Reference yield: 85.0%

trifluoromethane sulfonyl chloride (421-83-0) + diethyl malonate (105-53-3) → diethyl 2-chloromalonate (14064-10-9) + trifluoromethanesulfinic acid (34642-42-7)

Guidance literature:

diethyl malonate; With magnesium ethylate;

trifluoromethane sulfonyl chloride; In tetrahydrofuran;

DOI:10.1134/S1070428009090176

Reference yield: 75.0%

trifluoromethane sulfonyl chloride (421-83-0) + acetylacetone (123-54-6,81235-32-7) → trifluoromethanesulfinic acid (34642-42-7) + 3-chloropentane-2,4-dione (1694-29-7)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 10 - 50 ℃;

DOI:10.1134/S1070428009090176

upstream raw materials:

methanol

Benzyl Trifluoromethanesulfinate

p-Methylbenzyl Trifluoromethanesulfinate

p-Chlorobenzyl Trifluoromethanesulfinate

Downstream raw materials:

trimethylsilyl trifluoromethanesulfonate

Langlois reagent

trifluoromethan

CF₃S(O)OSn(CH₃)3