3470-38-0Relevant articles and documents
Diaryl triazenes inhibit cytochrome P450 1A1 and 1B1 more strongly than aryl morpholino triazenes
Moran, Rachel,Nakamura, Ryan,Isovitsch, Ralph,Iimoto, Devin
supporting information, (2022/01/24)
Several diaryl triazene derivatives were synthesized and tested for their ability to inhibit cytochrome P450 1A1 and 1B1 as a potential means to prevent and treat cancer. These compounds are more planar than their conformational flexible aryl morpholino t
Novel one-pot synthesis of thiophenols from related triazenes under mild conditions
Khazaei, Ardeshir,Kazem-Rostami, Masoud,Moosavi-Zare, Ahmadreza,Bayat, Mohammad,Saednia, Shahnaz
experimental part, p. 1893 - 1896 (2012/09/22)
In this work, at first, triazenes were synthesized from primary aryl amines. Afterwards, triazenes were converted into the corresponding thiophenols in one-pot using sodium sulfide in acidic media, by in situ generation of diazonium counterion beside hydrogen sulfide as anionic sulfur nucleophile at room temperature. The procedure can be a convenient shortcut for the preparation of thiophenols from primary aryl amines. Georg Thieme Verlag Stuttgart · New York.
Nitrosation with Sodium Hexanitrocobaltate(III)
Stefane, Bogdan,Kocevar, Marijan,Polanc, Slovenko
, p. 7165 - 7169 (2007/10/03)
Na3Co(NO2)6 has been investigated as a new reagent for the nitrosation of various substrates containing an amino functionality. Reactions took place in an aqueous solution of the reagent. The pH of the reaction mixture remained in the range 4.3-5. Thus, hydrazides were transformed to the corresponding acyl azides, and the reactions with arenesulfonyl hydrazines afforded arenesulfonyl azides. Treatment of aromatic amines with Na3Co(NO2)6 gave 1,3-diaryltriazenes in excellent yields; coupling of the initially formed diazo compound to the electron rich aromatic ring was also observed. Nitrosation of aliphatic amines was not possible due to complex formation with the reagent.