90401-84-6

Basic information

• Product Name: 6-CYANO-1-TETRALONE
• Synonyms: 6-CYANO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-ONE;6-CYANO-1-TETRALONE;5,6,7,8-Tetrahydro-5-oxo-2-naphthonitrile;5-Oxo-5,6,7,8-tetrahydronaphthalene-2-carbonitrile
• CAS NO: 90401-84-6
• Molecular Formula: C₁₁H₉NO
• Molecular Weight: 171.2
• Product Categories: Benzocycles
• Mol File: 90401-84-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 343℃
• Flash Point: 161℃
• Appearance: /
• Density: 1.19
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 6-CYANO-1-TETRALONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-CYANO-1-TETRALONE(90401-84-6)
• EPA Substance Registry System: 6-CYANO-1-TETRALONE(90401-84-6)

Safety Data

• Hazardous Substances Data: 90401-84-6(Hazardous Substances Data)

Usage

Uses

6-Cyano-1-tetralone is a reactant in the preparation of imidazolylmethylenetetrahydronaphthalene derivatives as aldosterone synthase inhibitors.

Upstream product

• 3470-53-9 6-amino-1-tetralone 
• 544-92-3 copper(I) cyanide 
• 151-50-8 potassium cyanide 
• 144464-64-2 5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl trifluoromethanesulfonate 
• 557-21-1 dicyanozinc 
• 3470-50-6 6-Hydroxy-1-tetralone 
• 1078-19-9 6-methoxy-3,4-dihydro-1(2H)-naphthalenone 
• 50878-03-0 N-(5,6,7,8-tetrahydronaphth-2-yl)acetamide 

Downstream Products

• 3470-46-0 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid 
• 321330-31-8 5-amino-5,6,7,8-tetrahydronaphthalene-2-carbonitrile 
• 952675-93-3 5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-7,8-dihydronaphthalene-2-carbonitrile 
• 828926-05-2 5(S)hydroxy-5,6,7,8-tetrahydronaphthalene-2-carbonitrile 
• 66362-06-9 C₂₀H₂₁NO₅S 
• 66362-09-2 C₁₈H₁₆N₂O₃S 
• 90401-85-7 ethyl 5-oxo-5,6,7,8-tetrahydronaphthalene-2-carboxylate 
• 1315479-99-2 (R,S)-5-hydroxy-5,6,7,8-tetrahydronaphthalene-2-carbonitrile 

Relevant articles and documents

AMINO ACID COMPOUNDS

[Problem] To provide novel compounds that are S1P1 receptor agonists and exhibit an immunosuppressive activities by inducing lymphocyte sequestration in secondary lymphoid tissues. In addition, to provide a pharmaceutical agent which comprises the compounds as an effective component, in particular to provide a therapeutic and/or prophylactic agent for an autoimmune disease and the like. [Solving Means] Amino acid compounds that are represented by the following Formula (1) are provided

Oxazolidone derivatives as PR modulators

Compounds of the following structure are described: wherein R1, R2, R5, R6, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful for treating a variety of hormone-related conditions including contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake or synchronizing estrus.

CYCLIC AMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF INFLAMMATION-RELATED DISORDERS MEDIATED BY BRADYKININ

Compounds of formula (I) are effective for treatment of pain and diseases, such as inflammation mediated diseases. The invention encompasses novel compounds, pharmaceutically acceptable derivatives thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving pain, inflammation mediated by Bradykinin. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes wherein q, t, R, Ra, Rb, Rc and R2 are as defined herein.