347362-36-1

Upstream product

• 652979-92-5 1,3-O-benzylidene-D-threitol 4-(t-butyldimethylsilyl) ether 
• 652979-94-7 1,3-O-benzylidene-D-erythrulose 4-(t-butyldimethylsilyl) ether 
• 99274-32-5 2,4-O-benzylidene-D-threose 
• 80924-06-7 1,3-O-benzylidene D-arabitol 
• 100-52-7 benzaldehyde 
• 81577-58-4 1,3-(R)-O-benzylidene-D-threitol 
• 652979-95-8 1,3-benzylidene-D-erythritol 4-(t-butyldimethylsilyl) ether 

Relevant academic research and scientific papers

Synthesis of methylerythritol phosphate analogues and their evaluation as alternate substrates for IspDF and IspE from Agrobacterium tumefaciens

The methylerythritol phosphate biosynthetic pathway, found in most Bacteria, some parasitic protists, and plant chloroplasts, converts d-glyceraldehyde phosphate and pyruvate to isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), where it

Synthesis of Enantiopure 2-C-Methyl-D-erythritol 4-Phosphate and 2,4-Cyclodiphosphate from D-Arabitol

(Equation presented) Two key intermediates of the newly discovered mevalonate-independent pathway for isoprenoid biosynthesis were prepared. Optically pure 2-C-methyl-D-erythritol 4-phosphate and 2,4-cyclodiphosphate were chemically synthesized from D-arabitol using a convenient benzylidene and tert-butyldimethylsilyl protection of polyhydroxylated intermediates. The new scheme offers a straightforward route to analogues and labeled forms.