Synthesis and biological activities of 2'-modified 4'-thionucleosides

Article abstract of DOI:10.1080/07328319708006142

We have synthesized 4'-thioDMDC, 4'-thiogemcitabine, and 4'- thioarabinonucleosides, as potential antitumor and antiviral agents, originated from D-glucose. Biological activities of these compounds are also described.

Full text of DOI:10.1080/07328319708006142

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Nucleosides and Nucleotides
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Synthesis and Biological Activities of
2′-Modified 4′-Thionucleosides
Yuichi Yoshimura a , Kenji Kitano a , Mikari Watanabe a , Hiroshi
Satoh a , Shinji Sakata a , Shinji Miura a , Noriyuki Ashida a ,
Haruhiko Machida a & Akira Matsuda b
a R & D Division , Yamasa Corporation , 2-10-1 Araoicho, Choshi,
Chiba, 288, Japan
b Faculty of Pharmaceutical Sciences , Hokkaido University ,
Kita-12, Nishi-6, Kita-ku, Sapporo, 060, Japan
Published online: 16 Aug 2006.
To cite this article: Yuichi Yoshimura , Kenji Kitano , Mikari Watanabe , Hiroshi Satoh , Shinji
Sakata , Shinji Miura , Noriyuki Ashida , Haruhiko Machida & Akira Matsuda (1997) Synthesis and
Biological Activities of 2′-Modified 4′-Thionucleosides, Nucleosides and Nucleotides, 16:7-9,
1103-1106, DOI: 10.1080/07328319708006142
To link to this article: http://dx.doi.org/10.1080/07328319708006142
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