34743-34-5

Basic information

• Product Name: N-(2,6-dimethylphenyl)-2-methylbenzamide
• Synonyms: N-(2,6-dimethylphenyl)-2-methylbenzamide
• CAS NO: 34743-34-5
• Molecular Formula: C₁₆H₁₇NO
• Molecular Weight: 239.31228
• Mol File: 34743-34-5.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(2,6-dimethylphenyl)-2-methylbenzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2,6-dimethylphenyl)-2-methylbenzamide(34743-34-5)
• EPA Substance Registry System: N-(2,6-dimethylphenyl)-2-methylbenzamide(34743-34-5)

Safety Data

• Hazardous Substances Data: 34743-34-5(Hazardous Substances Data)

Upstream product

• 529-20-4 2-methylphenyl aldehyde 
• 87-62-7 2,6-dimethylaniline 
• 933-88-0 ortho-toluoyl chloride 
• 7055-03-0 2-methyl-N-phenylbenzamide 
• 615-37-2 ortho-methylphenyl iodide 
• 201230-82-2 carbon monoxide 
• 118-90-1 ortho-methylbenzoic acid 

Downstream Products

• 34751-80-9 C₁₆H₁₇NOS 
• 34743-10-7 2-Methylthiobenzoyl-(2.6-dimethylanilid) 

Relevant articles and documents

N -Heterocyclic carbene (NHC) catalyzed amidation of aldehydes with amines via the tandem N -hydroxysuccinimide ester formation

A facile method for the amidation of aldehydes by a cascade approach was developed. This methodology, reported for the first time, uses a N-heterocyclic carbene (NHC) as the catalyst, and N-hydroxysuccinimide (NHS) mediated synthesis of amides utilising TBHP as the oxidant. Various substituted aldehydes reacted smoothly with NHS giving the corresponding active esters in moderate to good yields, which facilely converted into amides in one pot. In addition, the drug moclobemide was synthesized to represent the practical utility of the developed methodology. This journal is

A palladium-catalyzed carbonylation approach to acid chloride synthesis

We describe a new approach to acid chloride synthesis via the palladium-catalyzed carbonylation of aryl iodides. The combination of sterically encumbered phosphines (PtBu3) and CO coordination has been found to facilitate the rapid carbonylation of aryl iodides into acid chlorides via reductive elimination from (tBu3P)(CO) Pd(COAr)Cl. The formation of acid chlorides can also be exploited to perform traditional aminocarbonylation reactions under exceptionally mild conditions (ambient temperature and pressure), and with a range of weakly nucleophilic substrates.