34743-49-2

Usage

Uses

Used in Dye Industry:
4-methoxy-2,6-dimethyl-aniline is used as a chemical intermediate for the synthesis of various dyes. Its unique structure and properties make it a valuable component in the production of a wide range of dyes with different color characteristics and properties.
Used in Pharmaceutical Industry:
4-methoxy-2,6-dimethyl-aniline is used as a building block in the synthesis of various pharmaceutical compounds. Its presence in the molecular structure can influence the pharmacological properties, such as solubility, stability, and bioavailability, of the final drug product.
Used in Organic Synthesis:
4-methoxy-2,6-dimethyl-aniline is used as a versatile intermediate in the synthesis of other organic compounds. Its reactivity and functional groups make it suitable for various organic reactions, such as substitution, addition, and condensation, leading to the formation of a diverse range of organic molecules with different applications.

InChI:InChI=1/C9H13NO/c1-6-4-8(11-3)5-7(2)9(6)10/h4-5H,10H2,1-3H3

Upstream product

• 67-56-1 methanol 
• 3096-63-7 N-(2,6-dimethylphenyl)hydroxylamine 
• 61019-03-2 5-methoxy-1,3-dimethyl-2-nitrobenzene 
• 150370-06-2 1-(4-methoxy-2,6-dimethylphenyl)-2-phenyldiazene 
• 37621-81-1 sodium 3,5-dimethylphenolate 
• 77-78-1 dimethyl sulfate 
• 153968-41-3 (4-Methoxy-2,6-dimethyl-benzoyl)-phosphonic acid diethyl ester 
• 7664-93-9 sulfuric acid 
• 37934-89-7 2,6-Dimethyl-4-methoxybenzoic acid 
• 31247-59-3 2,6-dimethyl-4-methoxybenzoyl chloride 
• 1778-71-8 3,5-Dimethyl-4-phenylazo-phenol 
• 5344-97-8 3,5-dimethyl-4-nitrophenol 
• 4102-53-8 4-iodo-2,6-dimethylaniline 
• 3096-70-6 3,5-dimethyl-4-aminophenol 

Downstream Products

• 854053-65-9 2,6-dimethyl-[1,4]benzoquinone-4-(4-methoxy-2,6-dimethyl-phenylimine) 
• 527-61-7 2,6-dimethyl-1,4-benzoquinone 
• 2431-91-6 4-methoxy-2,6-dimethylphenol 
• 391201-50-6 bis-(4-methoxy-2,6-dimethyl-phenyl)-diazene-N,N'-dioxide 
• 32767-54-7 1-(2,6-Dimethyl-4-methoxy-phenyl)-3-phenyl-thioharnstoff 
• 130403-15-5 5-Methyl-isoxazole-3-carboxylic acid (4-methoxy-2,6-dimethyl-phenyl)-amide 
• 37934-89-7 2,6-Dimethyl-4-methoxybenzoic acid 
• 31247-59-3 2,6-dimethyl-4-methoxybenzoyl chloride 
• 1322877-99-5 C₂₂H₂₂ClN₅O₂ 
• 1352916-92-7 C₁₁H₁₄BrNO₂ 
• 1352916-97-2 C₂₁H₃₂N₂O 
• 1394159-52-4 (E,E)-N,N'-(pyridine-2,6-diylbis-(methanylylidene))bis(4-methoxy-2,6-dimethylaniline) 
• 1408250-57-6 C₁₈H₂₄BrN₃O₄ 
• 1352916-94-9 C₂₁H₃₀N₂O₂ 

Relevant academic research and scientific papers

B(C6F5)3-Catalyzed C-H Alkylation of N-Alkylamines Using Silicon Enolates without External Oxidant

An efficient method for the coupling of N-alkylamines with silicon enolates to generate β-amino carbonyl compounds is disclosed. These reactions proceed by activation of α-amino C-H bonds by B(C6F5)3, which likely generate

C-H Functionalization of Amines via Alkene-Derived Nucleophiles through Cooperative Action of Chiral and Achiral Lewis Acid Catalysts: Applications in Enantioselective Synthesis

Catalytic transformations of α-amino C-H bonds to afford valuable enantiomerically enriched α-substituted amines, entities that are prevalent in pharmaceuticals and bioactive natural products, have been developed. Typically, such processes are carried out

PYRAZOLOPYRIMIDINE DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION FOR USE IN PREVENTING OR TREATING CANCER, AUTOIMMUNE DISEASE AND BRAIN DISEASE CONTAINING THE SAME AS AN ACTIVE INGREDIENT

The present invention relates to a pyrazolopyrimidine derivative, a preparation method thereof and a pharmaceutical composition comprising the same as an active ingredient for the prevention or treatment of cancer, autoimmune disease and brain disease. The pyrazolopyrimidine derivative of the present invention exhibits excellent Bruton's tyrosine kinase inhibition activity, so that it can be effectively used as a pharmaceutical composition for the prevention or treatment of cancer, autoimmune disease and Parkinson's disease.

SULFONAMIDES AS GPR40- AND GPR120-AGONISTS

The invention relates to compounds acting as agonists of G-protein coupled receptor 120 (GPR120) and/or 40 (GPR40), and having formula (I). Said compounds are useful in the treatment of diseases or disorders modulated by GPR120 and/or GPR40 such as diabet

Efficient copper-catalyzed amination of DNA-conjugated aryl iodides under mild aqueous conditions

Herein, we describe the development of copper-catalyzed cross-coupling of DNA-conjugated aryl iodides with aliphatic amines. This protocol leverages a novel ligand, 2-((2,6-dimethoxyphenyl)amino)-2-oxoacetic acid, to effect the transformation in aqueous D

Selective Cross-Coupling of (Hetero)aryl Halides with Ammonia to Produce Primary Arylamines using Pd-NHC Complexes

Herein we report the first example of (hetero)arylation of ammonia using a monoligated palladium-NHC complex. The new, rationally designed, precatalyst (DiMeIHeptCl)Pd(allyl)Cl featuring highly branched alkyl chains has been shown to be effective in selective aminations across a range of challenging substrates, including nitrogen-containing heterocycles and those featuring base-sensitive functionality. The less bulky Pd-PEPPSI-IPentCl precatalyst performs well for ortho-substituted aryl halides, giving monoarylated products in high yield with good selectivity.

PYRIMIDINE COMPOUNDS AND PYRIMIDO INDOLE COMPOUNDS AND METHODS OF USE

The present invention discloses substituted pyrimidine and pyrimido indole compounds and optionally pharmaceutically acceptable salts, hydrates or solvates thereof. A method of treating a patient having cancer or a disease comprising administering to a patient an effective amount of the compound or pharmaceutically acceptable salt, hydrate, or solvate thereof.

Synthesis of 1,2-diaryl- and 1-aryl-2-alkylimidazoles with sterically demanding substituents

1,2-Diarylimidazoles are an important class of compounds. They are frequently used as ligands for photophysically active metal complexes and also display physiological activity. We developed a new, high-yielding procedure for the synthesis of 1,2-diaryl-s

Iron-catalyzed formation of 2-aminopyridines from diynes and cyanamides

Diynes and cyanamides undergo an iron-catalyzed [2 + 2 + 2] cycloaddition to form highly substituted 2-aminopyridines in an atom-efficient manner that is both high yielding and regioselective. This system was also used to cyclize two terminal alkynes and

Substituent effects on aromatic stacking interactions

Synthetic supramolecular zipper complexes have been used to quantify substituent effects on the free energies of aromatic stacking interactions. The conformational properties of the complexes have been characterised using NMR spectroscopy in CDCl3, and by comparison with the solid state structures of model compounds. The structural similarity of the complexes makes it possible to apply the double mutant cycle method to evaluate the magnitudes of 24 different aromatic stacking interactions. The major trends in the interaction energy can be rationalised using a simple model based on electrostatic interactions between the π-faces of the two aromatic rings. However, electrostatic interactions between the substituents of one ring and the π-face of the other make an additional contribution, due to the slight offset in the stacking geometry. This property makes aromatic stacking interactions particularly sensitive to changes in orientation as well as the nature and location of substituents. This journal is The Royal Society of Chemistry.