34856-94-5Relevant academic research and scientific papers
Reaction of vinyl triflates of α-keto esters with primary amines: Efficient synthesis of aziridine carboxylates
Tranchant, Marie-José,Dalla, Vincent,Jabin, Ivan,Decroix, Bernard
, p. 8425 - 8432 (2007/10/03)
Vinyl triflates of α-keto esters react smoothly with primary amines to provide aziridine carboxylates in good yields. In all cases, little or no stereoselectivity was observed. A mechanistic study has shown that aziridine carboxylates are strictly formed
Synthesis and stereochemistry of 1-alkyl-2-methoxycarbonyl-3-phenylaziridines
Eremeev,Semenikhina
, p. 724 - 726 (2007/10/02)
Mixtures of cis- and trans-1-alkyl-2-methoxycarbonyl-3-phenylaziridines are formed in the reaction of methyl α-bromocinnmate with excess amine, amino alcohol, and amino acid methyl ester hydrochloride. The ratios of the isomers depend on the solvent used.
