349546-52-7

Upstream product

• 42514-50-1 1-hydroxy-3-methylbut-3-ylamine 
• 128182-82-1 3-[Benzyloxycarbonylamino]-3-methylbutanoic acid,methyl ester 
• 597-43-3 2,2-dimethylsuccinic acid 
• 54043-71-9 4-methoxy-2,2-dimethyl-4-oxobutanoic acid 
• 349546-49-2 (3-hydroxy-1,1-dimethylpropyl)carbamic acid benzylester 
• 26939-09-3 2,4,4-trimethyl-5,6-dihydro-1,3(4H)-oxazine 
• 13139-17-8 N-(Benzyloxycarbonyloxy)succinimide 

Downstream Products

• 349546-55-0 ethyl (2E)-5-(benzyloxycarbonylamino)-5-methylhex-2-enoate 

Relevant academic research and scientific papers

Synthesis of N-protected 14C-labelled (2E)-5-amino-5-methylhex-2-enoic acid analogues

A novel method of preparing N-protected (2E)-5-amino-5-methylhex-2-enoic acids has been developed based on the synthesis of 3-methyl-3-amino-butanol. The method was used to synthesise 14C-labelled compounds of (1) via synthesis of triethylphosphono[1-14C]acetate.

MODULATORS OF HISTONE METHYLTRANSFERASE, AND METHODS OF USE THEREOF

Disclosed are compounds, pharmaceutical compositions containing the compounds, and the uses of the compounds and compositions as modulators of histone methyltransferases, and for treating diseases influenced by modulation of histone methyltransferase activity.