42514-50-1

Basic information

• Product Name: 3-AMINO-3-METHYL-BUTAN-1-OL
• Synonyms: 3-AMINO-3-METHYL-BUTAN-1-OL;3-Amino-3-methyl-1-butanol;3-Amino-3-methyl-butan-I-ol;1-butanol, 3-amino-3-methyl-
• CAS NO: 42514-50-1
• Molecular Formula: C₅H₁₃NO
• Molecular Weight: 103.16282
• EINECS: 255-865-9
• Product Categories: pharmacetical
• Mol File: 42514-50-1.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 179.2°Cat760mmHg
• Flash Point: 62.1°C
• Appearance: /
• Density: 0.918g/cm³
• Vapor Pressure: 0.285mmHg at 25°C
• Refractive Index: 1.451
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 15.42±0.10(Predicted)
• CAS DataBase Reference: 3-AMINO-3-METHYL-BUTAN-1-OL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-AMINO-3-METHYL-BUTAN-1-OL(42514-50-1)
• EPA Substance Registry System: 3-AMINO-3-METHYL-BUTAN-1-OL(42514-50-1)

Safety Data

• RIDADR: 2735
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 42514-50-1(Hazardous Substances Data)

Usage

General Description

3-Amino-3-methyl-butan-1-ol, also recognized under the IUPAC name as 3-Amino-3-methylbutan-1-ol, is a chemical compound whose formula is C5H13NO. It belongs to the class of organic compounds referred to as amino alcohols, which contain both an alcohol and an amine group. It's typically used in the production of other chemicals, serving as an intermediate in organic synthesis. Despite it being an amino alcohol which generally have varied toxicological effects on biological systems, its specific health or environmental impacts aren't widely studied or documented. Thus, it is always recommended to handle with caution until more concrete data becomes available. Scientific literature may refer to this compound under a few different names, indicating its different structural features.

InChI:InChI=1/C5H13NO/c1-5(2,6)3-4-7/h7H,3-4,6H2,1-2H3

Upstream product

• 625-05-8 3-amino-3-methylbutanoic acid 
• 766-15-4 4,4-dimethyl-1,3-dioxane 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 105090-72-0 3-azido-3-methylbutanoic acid 
• 541-47-9 3-Methylbutenoic acid 
• 6245-99-4 2,2-dimethyl-oxetane 
• 17945-55-0 3-Benzylamino-3-methyl-butan-1-ol 
• 26939-09-3 2,4,4-trimethyl-5,6-dihydro-1,3(4H)-oxazine 
• 624-96-4 1,3-dichloro-3-methylbutane 
• 7664-41-7 ammonia 
• 81548-18-7 3-acetamido-3-methyl-1-butanol 
• 102222-61-7 (3-Isocyano-3-methyl-butoxy)-trimethyl-silane 
• 37139-42-7 4,4-dimethyl-2-vinyl-4H-5,6-dihydro-1,3-oxazine 

Downstream Products

• 1019992-98-3 C₁₉H₂₃NO₃ 
• 187107-78-4 S-3-(benzyloxycarbonylamino)-3-methylbutyl ethanethioate 
• 1314079-85-0 C₂₁H₃₅NO₇S₂ 

Relevant articles and documents

Reaction of 4,4-dimethyl-1,3-dioxane with dinitriles

The reaction of 4,4-dimethyl-1,3-dioxane with bis(2-cyano)diethyl ether or 1,2-di(β-cyanoethoxy)-ethane yields the corresponding bis[2-(4,4-dimethyl-5,6-dihydro-2-oxazinyl)]diethyl ether and 1,2-di{β-[2-(4,4-dimethyl-5,6-dihydro-2-oxazinyl)]ethoxy} ethane

N,N-Dichloroaminosulfonic acids as novel topical antimicrobial agents

2-Dichloroamino-2-methyl-propane-1-sulfonic acid sodium salt (2a), a stable derivative of endogenous N,N-dichlorotaurine (1), has been identified and is under development as a topical antimicrobial agent. Structure-activity relationships of analogs were explored to achieve optimal antimicrobial activity with minimal mammalian toxicity while maintaining the desired stability. All the analogs synthesized showed antimicrobial activity against Staphylococcus aureus, Escherichia coli, and Candida albicans in the range of 1-128 μg/mL and cytotoxicity against mammalian L929 cells in the range 80-1900 μg/mL.

Aminoquinolones as GSK-3 inhibitors

Provided herein are aminoquinolones and pharmaceutically acceptable derivatives thereof. In certain embodiments, provided herein are compounds, compositions and methods for treating, preventing or ameliorating GSK-3 mediated diseases.