350-35-6

Basic information

• Product Name: 1-(P-FLUOROPHENYL)-1,2-DIBROMOETHANE
• Synonyms: 1-(P-FLUOROPHENYL)-1,2-DIBROMOETHANE;1-(1,2-Dibromoethyl)-4-fluorobenzene
• CAS NO: 350-35-6
• Molecular Formula: C₈H₇Br₂F
• Molecular Weight: 281.95
• Mol File: 350-35-6.mol
• Article Data: 20

Chemical Properties

• Boiling Point: 253.1°Cat760mmHg
• Flash Point: 106.9°C
• Appearance: /
• Density: 1.835g/cm³
• Vapor Pressure: 0.0297mmHg at 25°C
• Refractive Index: 1.582
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 1-(P-FLUOROPHENYL)-1,2-DIBROMOETHANE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(P-FLUOROPHENYL)-1,2-DIBROMOETHANE(350-35-6)
• EPA Substance Registry System: 1-(P-FLUOROPHENYL)-1,2-DIBROMOETHANE(350-35-6)

Safety Data

• Hazardous Substances Data: 350-35-6(Hazardous Substances Data)

Usage

General Description

1-(p-fluorophenyl)-1,2-dibromoethane is a chemical compound that is made up of a fluorophenyl group and two bromine atoms attached to an ethane molecule. It is commonly used in organic synthesis and research as a reagent for various chemical reactions. The compound is known for its high reactivity and ability to undergo substitution and elimination reactions. It is also used in the production of pharmaceuticals, agrochemicals, and other industrial products. However, it is important to handle this compound with caution, as it may pose health and environmental hazards if not used and disposed of properly.

InChI:InChI=1/C8H7Br2F/c9-5-8(10)6-1-3-7(11)4-2-6/h1-4,8H,5H2

Upstream product

• 332-42-3 (2-bromoethyl)-4-fluorobenzene 
• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 405-99-2 para-fluorostyrene 

Downstream Products

• 36716-76-4 4-(p-fluorophenyl)-3-cyclohexen-1-ol 
• 365-23-1 1-fluoro-4-(1-(p-tolyl)vinyl)benzene 
• 32687-34-6 3-(4-fluorobenzene)-2H-azirine 
• 405-99-2 para-fluorostyrene 
• 403-29-2 2-bromo-4'-fluoroacetophenone 
• 1414365-78-8 1-benzyl-4-(4-fluorophenyl)-2-phenyl-1H-imidazole 
• 1374152-38-1 1-(1-azidovinyl)-4-fluorobenzene 
• 1301266-96-5 4-fluorophenylvinylboronic acid 
• 1621387-07-2 2-((1-(4-fluorophenyl)vinyl)oxy)isoindoline-1,3-dione 

Relevant articles and documents

Dihalogenation of Alkenes Using Combinations of N-Halosuccinimides and Alkali Metal Halides

A simple, efficient and eco-friendly method for the vicinal dihalogenation of alkenes is described. The reaction is performed with a combination of a N-halosuccinimide and an alkali metal halide using environmentally benign solvents such as acetic acid an

Electrosynthesis of N-unsubstituted enaminosulfones from vinyl azides and sodium sulfinates mediated by NH4I

A wide range of N-unsubstituted enaminosulfones were obtained via electrochemical sulfonylation of vinyl azides with sulfonyl radicals generated from sodium sulfinates. The discovery of N-unsubstituted enaminosulfones synthesis is based on a unique ability of the azido group to eliminate the N2 molecule. The process is performed under constant current conditions in an experimentally convenient undivided electrochemical cell equipped with a graphite anode and a stainless steel cathode applying NH4I both as the redox catalyst and the supporting electrolyte.

Asymmetric Nazarov Cyclizations of Unactivated Dienones by Hydrogen-Bond-Donor/Lewis Acid Co–Catalyzed, Enantioselective Proton-Transfer

We report an enantioselective Nazarov cyclization catalyzed by chiral hydrogen-bond-donors in concert with silyl Lewis acids. The developed transformation provides access to tri-substituted cyclopentenones in high levels of enantioselectivity (up to 95% e.e.) from a variety of simple unactivated dienones. Kinetic and mechanistic studies are consistent with a reversible 4π-electrocyclization C?C bond-forming step followed by rate- and enantio-determining proton-transfer as the mode of catalysis. (Figure presented.).