3506-37-4Relevant articles and documents
LDA-Promoted Synthesis of 3-Amino Furans by Selective Lithiation of Enaminones
Kong, Lingkai,Shao, Yushang,Li, Yanli,Liu, Yuanyuan,Li, Yanzhong
, p. 12641 - 12645 (2015)
An efficient cascade β-metalation/addition/cyclization reaction promoted by LDA is described in which 3-amino furans were constructed from enaminones and aldehydes. A broad range of substituents on the starting compounds was tolerated, and the polysubstit
Stereoselective synthesis of trifluoromethyl-substituted 2: H -furan-amines from enaminones
Liang, Xiaoyu,Guo, Pan,Yang, Wenjie,Li, Meng,Jiang, Chengzhou,Sun, Wangbin,Loh, Teck-Peng,Jiang, Yaojia
supporting information, p. 2043 - 2046 (2020/02/22)
A straightforward strategy for synthesis of highly functionalized trifluoromethyl 2H-furans is described. The copper catalyzed method relies on a cascade cyclic reaction between enaminones and N-tosylhydrazones. This method allows the synthesis of 2-amino
Fe-Catalyzed enaminone synthesis from ketones and amines
Wu, Wenfeng,Wang, Zhuxian,Shen, Qun,Liu, Qiang,Chen, Huoji
supporting information, p. 6753 - 6756 (2019/07/22)
We have developed an iron-catalyzed direct olefination for enaminone synthesis, with saturated ketones as a source of olefins. This direct ketone β-functionalization reaction has readily available starting materials and a wide range of substrates and requires mild reaction conditions.