952-51-2

Basic information

• Product Name: r-[2-(1-piperidinyl)ethyl]-
• CAS NO: 952-51-2
• Molecular Weight: 219.327
• Mol File: 952-51-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: r-[2-(1-piperidinyl)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: r-[2-(1-piperidinyl)ethyl]-(952-51-2)
• EPA Substance Registry System: r-[2-(1-piperidinyl)ethyl]-(952-51-2)

Safety Data

• Hazardous Substances Data: 952-51-2(Hazardous Substances Data)

Upstream product

• 73-63-2 1-phenyl-3-(piperidin-1-yl)propan-1-one 
• 886-06-6 1-phenyl-3-piperidino-propan-1-one; hydrochloride 
• 110-89-4 piperidine 
• 4436-23-1 2-phenyloxetane 
• 18776-12-0 3-chloro-1-phenyl-propan-1-ol 
• 93-54-9 1-Phenyl-1-propanol 
• 3506-37-4 (E)-1-phenyl-3-(piperidin-1-yl)prop-2-en-1-one 
• 936-59-4 3-chloropropiophenone 
• 62872-58-6 3-iodo-1-phenyl-propan-1-ol 
• 879-72-1 3-(dimethylamino)propiophenone hydrochloride 
• 185245-65-2 3-methylthio-3-N-piperidino-1-phenyl-2-propen-1-one 

Downstream Products

• 95294-69-2 2-phenyloctahydropyrido[2,1-b][1,3]oxazine 
• 3339-05-7 1-(3-chloro-3-phenylpropyl)piperidine hydrochloride 
• 1373610-97-9 1-(3-phenyl-3-(4-(trifluoromethyl)phenoxy)propyl)piperidine 
• 4810-93-9 N-(3-Phenyl-3-hydroxypropyl)-valerolactam 
• 42065-01-0 1-(3-chloro-3-phenyl-propyl)-piperidine 
• 25243-61-2 acetic acid-(1-phenyl-3-piperidino-propyl ester) 

Relevant articles and documents

Electrooxidative cyclization of hydroxyamino compounds possessing a benzyl group

Several novel 2-aryl-1,3-oxazinane and 2-aryl-1,3-oxazolidine derivatives were synthesized from N-benzyl-2-piperidineethanols and N-benzyl-2- piperidinemethanols, respectively, by using electrooxidative methods in methanol. For these reactions, the yields of the corresponding cyclized compounds were significantly increased by using catalytic amounts of iodide ions. In contrast, 3-dialkylamino-1-phenylpropanols afforded the expected cyclic 6-phenyl-1,3-oxazinane derivatives using only a small excess of base. Georg Thieme Verlag Stuttgart · New York.

Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols

A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols. Georg Thieme Verlag Stuttgart · New York.

Intramolecular Quenching of Iminium Ions Generated by Photooxidation of Aminoalcohols with Ketones. A New Synthesis of Oxazines and Oxazoles

The irradiation of tertiary amines in the presence of ketones leads to a regioselective and stereoselective formation of iminium salts which then react to afford the corresponding oxazines or oxazoles. - Key words : Ammoniumyl ions, iminium ions, electron transfer, amines, ketones, tetrahydrooxazine tetrahydrooxazoles.