35094-91-8

Usage

Uses

Used in Pharmaceutical Industry:
4-(4-METHYLPHENOXY)PHENOL is used as an intermediate in the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs with potential therapeutic applications.
Used in Dye Industry:
4-(4-METHYLPHENOXY)PHENOL is used as a precursor in the production of dyes. Its chemical properties make it suitable for creating a wide range of colors, which can be used in various applications such as textiles, plastics, and printing inks.
Used in Polymer Industry:
4-(4-METHYLPHENOXY)PHENOL is used in the synthesis of polymers. Its ability to form stable bonds with other molecules makes it a valuable component in the creation of new polymer materials with specific properties.
Used in Plastics and Adhesives Industry:
4-(4-METHYLPHENOXY)PHENOL is used as a UV absorber in plastics, adhesives, and personal care products. Its ability to absorb ultraviolet radiation helps protect these materials from degradation and extends their lifespan.
Used in Personal Care Products Industry:
4-(4-METHYLPHENOXY)PHENOL is used as a UV absorber in personal care products, such as sunscreens and cosmetics. Its inclusion in these products helps protect the skin from harmful UV rays, reducing the risk of sunburn and skin damage.
Used in Antimicrobial Materials Production:
4-(4-METHYLPHENOXY)PHENOL has antibacterial and antifungal properties, making it useful in the production of antimicrobial materials. Its ability to inhibit the growth of microorganisms can be utilized in various applications, such as medical devices, food packaging, and water treatment systems.
Safety Precautions:
Due to its potential health hazards, 4-(4-METHYLPHENOXY)PHENOL should be handled and stored with caution, following appropriate safety measures. This includes wearing protective clothing, using proper ventilation, and adhering to guidelines for safe handling and disposal of chemicals.

Upstream product

• 3402-85-5 1-methoxy-4-(p-tolyloxy)benzene 
• 95872-23-4 2,4,6-tri-t-butyl-4-(4'-methylphenoxy)cyclohexa-2,5-dienone 
• 459-57-4 4-fluorobenzaldehyde 
• 106-44-5 p-cresol 
• 61343-83-7 4-(4-methylphenoxy)benzaldehyde 
• 10034-85-2 hydrogen iodide 
• 1034-10-2 DL-thyronine 

Downstream Products

• 139034-84-7 2-chloro-4-p-tolyloxy-phenol 
• 20185-63-1 1-acetoxy-4-p-tolyloxy-benzene 
• 40843-28-5 2-(4-p-Tolyloxy-phenoxy)-propionic acid 
• 592508-72-0 4-(4'-methylphenoxy)phenyl allyl ether 
• 1003960-02-8 tert-butyl 2-methyl-2-((4-(p-tolyloxy)phenyl)oxy)propanoate 
• 656233-18-0 2-imino-5-{4-[3-(2-propyl-4-p-tolyloxy-phenoxy)-propoxy]-phenyl}-thiazolidin-4-one 
• 592508-47-9 hydroxy-{4-[3-(2-propyl-4-p-tolyloxy-phenoxy)-propoxy]-phenyl}-acetic acid methyl ester 
• 228578-10-7 2-Propyl-4-(4'-methylphenoxy)phenol 

Relevant academic research and scientific papers

Quinoline derivative as well as preparation method and application thereof (by machine translation)

The invention provides a quinoline derivative and a composition containing the same. The invention also provides a method for preparing the derivative and application of the derivative and the composition to kill pests. (by machine translation)

SUBSTITUTED IMIDAZOLONE DERIVATIVES, PREPARATIONS AND USES

The present invention relates to polysubstituted imidazolone derivatives, to the pharmaceutical compositions comprising them and to the therapeutic uses thereof in the human and animal health fields. The present invention also relates to a process for preparing these derivatives.

BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION

The present invention relates to a chemical genus of biaryl substituted heterocycle inhibitors of LTA4H (leukotriene A4 hydrolase) useful for the treatment and prevention and prophylaxis of inflammatory diseases and disorders. The compounds have general formula Ψ: An example is

ARYLTHIAZOLIDINEDIONE DERIVATIVES

Substituted 5-aryl-2,4-thiazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR alpha , delta and/or gamma mediated diseases, disorders and conditions.

5-Aryl thiazolidine-2,4-diones as selective PPARγ agonists

A series of 5-aryl thiazolidine-2,4-diones containing 4-phenoxyphenyl side chains was designed, synthesized, and evaluated for PPAR agonist activities. One such compound 28 exhibited comparable levels of glucose correction to rosiglitazone in the db/db mouse type 2 diabetes animal model.

Arylthiazolidinedione and aryloxazolidinedione derivatives

Substituted 5-aryl-2,4-thiazolidinediones or 5-aryl-2,4-oxazolidinediones that also carry a second substituent in the 5-position of the heterocyclic ring are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR α, δ and/or γ mediated diseases, disorders and conditions.

Arylthiazolidinedione derivatives

Substituted 5-aryl-2,4-thiazolidinediones are potent agonists of PPAR, and are therefore useful in the treatment, control or prevention of diabetes, hyperglycemia, hyperlipidemia (including hypercholesterolemia and hypertriglyceridemia), atherosclerosis, obesity, vascular restenosis, and other PPAR α, δ and/or γ mediated diseases, disorders and conditions.

CHOLESTEROL ESTER HYDROLASE INHIBITORS

The compounds of the formula: in which R1 is alkyl of 4 or more carbon atoms, cycloalkyl, 1-adamantyl, 2-adamantyl, 3-noradamantyl, 3-methyl-1-adamantyl, 1-fluorenyl, 9-fluorenyl, cycloalkylalkyl, phenyl, substituted phenyl, alkyl, alkoxy, halo, nitro, cyano or trifluoromethyl, phenylalkyl or substituted phenylalkyl, where the substituent on the benzene ring is alkyl, alkoxy, halo, nitro, cyano, trifluoromethyl or phenyl; R2 is hydrogen, alkyl or R1 taken with R2 and the nitrogen atom to which they are attached form a heterocyclic moiety of the formula: wherein in which R7 is hydrogen, alkyl, hydroxy, alkanoyloxy, hydroxyalkyl, hydroxycarbonyl, alkoxycarbonyl, phenyl or substituted phenyl, in which the substituent is alkyl, alkoxy, halo, nitro, cyano, haloalkyl, perhaloalkyl or dialkylaminoalkyl; R8 is hydrogen or alkyl or R7 and R8 taken together are polymethylene; R9 is hydrogen, alkyl, phenyl or substituted phenyl, in which the substituent is alkyl, alkoxy, halo, nitro, cyano or perhaloalkyl; R10 is hydrogen, alkyl or gemdialkyl; n is one of the integers 0, 1 or 2; and R3, R4, R5 and R6 are, independently, hydrogen, alkyl, alkoxy, halo, nitro, cyano or perhaloalkyl, alkoxycarbonyl or hydroxycarbonyl; and when X is --NR9-- or R7 is an amino alkyl group, a pharmaceutically acceptable salt thereof; useful as inhibitors of cholesterol ester hydrolase

4-SUBSTITUTED PIPERIDINECARBOXYLIC ACID ESTERS: INHIBITION OF CHOLESTEROL ABSORPTION

Inhibition of the enzymes cholesterol ester hydrolase (CEH) and/or acyl coenzyme A: cholesterol acyltransferase (ACAT) results in inhibition of absorption of cholesterol and thus lowers serum cholesterol levels. Compounds of the formula below: where R1 is

Polimerisation and Related Reactions involving Nucleophilic Aromatic Substitution. Part 2. The Rates of Reaction of Substituted 4-Halogenobenzophenones with the Salts of Substituted Hydroquinones

4-X-4'-fluorobenzophenones undergo the expected nucleophilic substitution reactions with the alkali metal salts of 4-Y-4'-hydroxydiphenyl ethers at 140 deg C in diphenyl sulphone as solvent: the Hammett ρ value is 1.02 for the X substituents and -0.34 for the Y substituents.The order of reactivity of the alkali metal salts is Cs > K > Na.The related reaction of fluorobenzophenone with potassium 4-Z-phenolates under the same conditions gives a ρ value of -2.28.This result has been used to calculate the corresponding rate coefficients for the reaction of the mono- and di-potassium salts of hydroquinone with fluorobenzophenone.