35133-77-8Relevant articles and documents
Copper-catalyzed cross-coupling of 1-iodoalkynes with organostannanes
Kang, Suk-Ku,Kim, Won-Yeob,Jiao, Xianghua
, p. 1252 - 1254 (1998)
Copper-catalyzed cross-coupling of 1-iodoalkynes with organostannanes was readily achieved in the presence of CuI (10 mol%) in DMF at room temperature for 6 hours by adding 1-iodoalkynes slowly to organostannanes.
Simple and efficient diaryl alkyne synthesis method
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Paragraph 0026; 0029-0031, (2021/04/14)
The embodiment of the invention discloses a simple and efficient diaryl alkyne synthesis method. The method comprises the steps of by taking arylmethylbenzotriazole and aromatic aldehyde as raw materials, carrying out addition and double-beta-elimination reaction under the action of bis (trimethylsilyl) amino salt MN (SiMe3) 2 to synthesize diaryl alkyne by a one-pot method. The raw materials and chemical reagents used in the method are easy to obtain, the reaction conditions are mild, the operation is simple, the substrate universality is good, the product yield is high, and the method is a simple and efficient diaryl alkyne synthesis method.
Sustainable dipolar homo-dicopper (II) dihydrazone complex as a catalyst for Sonogashira cross couplings
Adam, Mohamed Shaker S.
, (2019/11/02)
A novel dicopper (II) complex, Cu2L, was prepared form the complexation of the new polydentate ligand (H4L), bis(sodium 3-formyl-4-hydroxybenzenesulfonate)succinylhydrazone, with copper acetate. The novel homobinuclear complex was quite characterized by various physico-chemical tools and employed as a homogeneous and efficient-green catalyst for Sonogashira cross-couplings of phenylacetylene with halobenzenes under sustainable conditions. Cu2L exhibited very good catalytic performance with excellent chemoselectivity. The catalytic efficiency of Cu2L was improved by using ionic liquids–aqueous media (1: 1, binary mixture). A mechanistic pathway was also proposed for Cu(II)-catalyzed Sonogashira cross-coupling reactions for the reported finding. DFT for H4L and Cu2L were studied. Electronic configurations, energy of HOMO and LUMO orbitals, energy gap between orbitals (ΔE), electronegativity, hardness and softness were also calculated and compared with the applicable catalytic findings of Cu2L, which are in good conformity.
