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351899-02-0

2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE is a chemical compound with the molecular formula C16H11BrN2O2. It is a hydrazide derivative of quinoline carboxylic acid, characterized by a quinoline ring system with a bromo-phenyl substituent and a carboxylic acid hydrazide functional group. 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE is commonly used in organic synthesis and pharmaceutical research, and is recognized for its potential as a versatile intermediate in the development of new chemical entities.

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  • 351899-02-0 Structure

  • Basic information

    1. Product Name: 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE
    2. Synonyms: 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE;2-(4-bromophenyl)-4-quinolinecarbohydrazide;2-(4-bromophenyl)cinchoninohydrazide;2-(4-bromophenyl)-4-Quinolinecarboxylic acid hydrazide
    3. CAS NO:351899-02-0
    4. Molecular Formula: C16H12BrN3O
    5. Molecular Weight: 342.19
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 351899-02-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE(351899-02-0)
    11. EPA Substance Registry System: 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE(351899-02-0)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: IRRITANT
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 351899-02-0(Hazardous Substances Data)

351899-02-0 Usage

Uses

Used in Pharmaceutical Research:
2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE is used as a precursor in the synthesis of various pharmaceutical agents and organic compounds. Its unique structure and reactivity make it a valuable compound in the field of medicinal chemistry and drug discovery, contributing to the development of new therapeutic agents.
Used in Organic Synthesis:
In the field of organic synthesis, 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE serves as a key intermediate for the creation of a wide range of organic compounds. Its presence in the synthesis process allows for the formation of complex molecules with potential applications in various industries.
Used in Medicinal Chemistry:
2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE is utilized in medicinal chemistry for its potential to contribute to the discovery and development of new drugs. Its structural features make it a promising candidate for the design of novel pharmaceuticals with improved efficacy and selectivity.
Used in Drug Discovery:
In the realm of drug discovery, 2-(4-BROMO-PHENYL)-QUINOLINE-4-CARBOXYLIC ACID HYDRAZIDE is employed as a component in the screening and evaluation of potential drug candidates. Its properties and reactivity are instrumental in identifying and optimizing compounds with therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 351899-02-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,8,9 and 9 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 351899-02:
(8*3)+(7*5)+(6*1)+(5*8)+(4*9)+(3*9)+(2*0)+(1*2)=170
170 % 10 = 0
So 351899-02-0 is a valid CAS Registry Number.

351899-02-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(4-bromophenyl)quinoline-4-carbohydrazide

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
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More Details:351899-02-0 SDS

351899-02-0Relevant articles and documents

New quinoline-based heterocycles as anticancer agents targeting Bcl-2

Hamdy, Rania,Elseginy, Samia A.,Ziedan, Noha I.,Jones, Arwyn T.,Westwell, Andrew D.

, (2019/04/05)

The Bcl-2 protein has been studied as an anticancer drug target in recent years, due to its gatekeeper role in resisting programmed cancer cell death (apoptosis), and the design of BH3 domain mimetics has led to the clinical approval of Venetoclax (ABT-19

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