35225-01-5

Basic information

• Product Name: 5-(3-chlorophenyl)-1H-1,2,3-triazole
• Synonyms: 5-(3-chlorophenyl)-1H-1,2,3-triazole
• CAS NO: 35225-01-5
• Molecular Formula: C₈H₆ClN₃
• Molecular Weight: 179.60634
• Mol File: 35225-01-5.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-(3-chlorophenyl)-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-chlorophenyl)-1H-1,2,3-triazole(35225-01-5)
• EPA Substance Registry System: 5-(3-chlorophenyl)-1H-1,2,3-triazole(35225-01-5)

Safety Data

• Hazardous Substances Data: 35225-01-5(Hazardous Substances Data)

Upstream product

• 766-83-6 m-chlorophenylacetylene 
• 4648-54-8 trimethylsilylazide 
• 5431-97-0 (2RS:3SR)-2,3-dibromo-3-(3-chloro-phenyl)-propionic acid 
• 37888-03-2 3-chloroβ-nitrostyrene 
• 587-04-2 m-Chlorobenzaldehyde 
• 75-52-5 nitromethane 
• 99-02-5 3'-Chloroacetophenone 
• 873-63-2 m-chlorobenzyl alcohol 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 1013479-86-1 N'-(1-(3-chlorophenyl)ethylidene)-4-methylbenzenesulfonohydrazide 

Downstream Products

• 1594930-56-9 C₁₉H₁₅ClN₄ 
• 1594929-76-6 2-(1-benzyl-1H-pyrrol-2-yl)-4-(3-chlorophenyl)-2H-1,2,3-triazole 
• 1594930-04-7 C₂₃H₁₇ClN₄ 
• 1594929-16-4 1-benzyl-2-(4-(3-chlorophenyl)-2H-1,2,3-triazol-2-yl)-1H-indole 
• 1378976-28-3 4-(3-chlorophenyl)-1-methyl-1H-1,2,3-triazole 
• 1378976-27-2 5-(3-chlorophenyl)-1-methyl-1H-1,2,3-triazole 

Relevant articles and documents

Direct Synthesis of 4-Aryl-1,2,3-triazoles via I2-Promoted Cyclization under Metal- And Azide-Free Conditions

We herein report an iodine-mediated formal [2 + 2 + 1] cyclization of methyl ketones, p-toluenesulfonyl hydrazines, and 1-aminopyridinium iodide for preparation of 4-aryl-NH-1,2,3-triazoles under metal- and azide-free conditions. Notably, this is achieved

1, 4-Diazabicyclo[2.2.2]octane-sulfonic acid immobilized on magnetic Fe3O4?SiO2 nanoparticles: a novel and recyclable catalyst for the one-pot synthesis of 4-aryl-NH-1, 2, 3-triazoles

Abstract: In this study, the surface of silica-coated magnetic nanoparticles (Fe3O4?SiO2) were successfully functionalized by an organic ligand of 1, 4-Diazabicyclo[2.2.2]octane (DABCO)-sulfonic acid and used as a highly efficient catalyst for the synthesis of 4-aryl-NH-1, 2, 3-triazoles from the benzyl alcohol derivatives, nitromethane and sodium azide in ethanol. Furthermore, this catalyst could be recovered and reused five times without noticeable loss of activity. Graphic Abstract: Fe3O4?SiO2?TCT-DABCO-SO3H nanoparticles were successfully synthesized and used as a novel, recyclable, efficient and heterogeneous catalyst for the synthesis of 4-aryl-NH-1, 2, 3-triazoles.[Figure not available: see fulltext.]

Metal-Free Cascade [4 + 1] Cyclization Access to 4-Aryl- NH-1,2,3-triazoles from N-Tosylhydrazones and Sodium Azide

A molecular iodine-mediated coupling cyclization reaction for the synthesis of 4-aryl-NH-1,2,3-triazoles has been developed from N-tosylhydrazones and sodium azide. This metal-free cascade [4 + 1] cyclization reaction could rapidly synthesize valuable com