35247-24-6

Basic information

• Product Name: 1-Pyrrolidinepropanoic acid, b-oxo-, ethyl ester
• CAS NO: 35247-24-6
• Molecular Formula: C9H15NO3
• Molecular Weight: 185.223
• Mol File: 35247-24-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Pyrrolidinepropanoic acid, b-oxo-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolidinepropanoic acid, b-oxo-, ethyl ester(35247-24-6)
• EPA Substance Registry System: 1-Pyrrolidinepropanoic acid, b-oxo-, ethyl ester(35247-24-6)

Safety Data

• Hazardous Substances Data: 35247-24-6(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 

Downstream Products

• 65651-80-1 ethyl (E)-3-(pyrrolidin-1-yl)acrylate 
• 6317-35-7 ethyl 3-tetrahydro-1H-1-pyrrolilpropanoate 
• 71509-21-2 4-(4-chloro-butylamino)-6-phenyl-6H-pyrano[3,2-c]quinoline-2,5-dione 

Relevant articles and documents

Transacylation of α-Aryl-β-keto Esters

The acyl group of an α-aryl-β-keto ester was readily transferred to N-, O-, and S-nucleophiles. The transacylation from arylated diethyl 3-oxoglutarate to amines led to unsymmetrical malonic acid amide esters in high yields. The present reaction proceeded under mild conditions without formation of detectable byproducts. Only simple experimental manipulations were required. This reaction was also found to be sensitive to steric factors, which enabled the chemoselective monoacylation of diamines and amino alcohols without any modifications such as protection.