35287-01-5

Upstream product

• 3768-56-7 1-(trimethylsilyl)piperidine 
• 104-87-0 4-methyl-benzaldehyde 
• 110-89-4 piperidine 
• 113700-15-5 1-(Bromo-p-tolyl-methyl)-pyridinium; bromide 

Downstream Products

• 110-89-4 piperidine 
• 35278-95-6 N,N-piperidyl-1-p-tolylmethanamine 
• 35278-89-8 4-(4-methylphenyl)-4-piperidino-1-butene 
• 132637-68-4 1-(phenyl(p-tolyl)methyl)piperidine 
• 252365-45-0 N-(4,4'-dimethyl)benzhydrylpiperidine 

Relevant academic research and scientific papers

N-(1-Haloalkyl)pyridinium Salts: Preparation and Use for New Syntheses of Other N-(1-Substituted-alkyl)pyridinium Salts, N,N'-(1-Alkylidene)bisamines, and N,N'-(1-Alkylidene)bisbenzazoles

N-(1-Haloalkyl)pyridinium halides, obtained from an aldehyde, a thionyl halide, and pyridine, react readily with nucleophiles to yield N-(1-substituted -alkyl)pyridinium salts.N-(1-Bromoalkyl)pyridinium bromides rect readily with a wide range of nucleophiles to replace either the halogen ( by 1 mol ) or both halogen and pyridinium ( 2 mol ).They are useful precursors for the preparation of bisbenzazoles and other aminals under neutral and mild conditions.

Trimethylsilylamines III: mise en evidence du compose d'addition sur les aldehydes; preparation d'aminals et de β-dialkylamino β-arylesters en milieu aprotique

Dialkylaminotrimethylsilanes react with aromatic aldehydes using trimethylsilyltriflate and tetrabutylammonium fluoride as catalysts and lead quantitatively to the corresponding aminals in aprotic media.The intermediate silylated hemiaminal can be characterized in many cases, mainly with pyridinecarbaldehydes.Aminals are obtained from aliphatic aldehydes using fluoride ion as catalyst.A one-pot synthesis of some β-dialkylamino β-arylesters from these reagents is described.