3532-35-2Relevant articles and documents
Microwave-Accelerated N-Acylation of Sulfoximines with Aldehydes under Catalyst-Free Conditions
Ambala, Srinivas,Arvidsson, Per I.,Govender, Thavendran,Kruger, Hendrik G.,Naicker, Tricia,Rajbongshi, Kamal K.
, p. 1279 - 1286 (2020)
An efficient catalyst-free radical cross-coupling reaction between aromatic aldehydes and sulfoximines was developed. The reaction took place in the presence of N-bromosuccinimide as the radical initiator under microwave irradiation to afford the corresponding acylated sulfoximines in moderate to excellent yields (27 examples). This protocol proved to be rapid, easy to handle, and applicable to a broad scope of substrates.
Copper-catalyzed oxidative decarboxylative coupling of α-keto acids and sulfoximines
Pimpasri, Chaleena,Sumunnee, Ladawan,Yotphan, Sirilata
, p. 4320 - 4327 (2017/07/10)
A copper-catalyzed oxidative decarboxylative coupling of α-keto acids with NH-sulfoximines has been developed. With CuBr as the catalyst and K2S2O8 as the oxidant, this reaction enables the formation of a C-N bond and gives N-aroylsulfoximine products in moderate to excellent yields. The reaction mechanism is likely to involve the generation of a reactive aroyl radical intermediate.
