354-87-0

Usage

Uses

Used in Pharmaceutical Industry:
1,1,2,2,2-Pentafluoroethanesulfonyl fluoride is used as a chemical intermediate for the synthesis of various pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing ones.
Used in Agrochemical Industry:
In the agrochemical industry, 1,1,2,2,2-pentafluoroethanesulfonyl fluoride is utilized as a building block for the production of agrochemicals, enhancing the performance and selectivity of these compounds in agricultural applications.
Used in Specialty Chemicals Production:
1,1,2,2,2-Pentafluoroethanesulfonyl fluoride is employed as a key intermediate in the synthesis of specialty chemicals, which are used in a wide range of applications, including coatings, adhesives, and advanced materials.
Used in Fluorinated Compounds Synthesis:
As a highly fluorinated compound, 1,1,2,2,2-pentafluoroethanesulfonyl fluoride is used as a starting material for the synthesis of various fluorinated compounds, which possess unique properties and are valuable in numerous industrial and research applications.

InChI:InChI=1/C2F6O2S/c3-1(4,5)2(6,7)11(8,9)10

Upstream product

• 81363-76-0 propane-2-sulfonamide 
• 1520-70-3 Ethanesulfonamide 
• 3518-66-9 1-chloro-ethanesulfonyl chloride 
• 354-88-1 perfluoroethanesulfonic acid 
• 7664-39-3 hydrogen fluoride 
• 110073-91-1 propane-1,3-disulfonyl difluoride 
• 2127-74-4 1,2,2,2-tetrafluoro-ethanesulfonyl fluoride 

Downstream Products

• 354-88-1 perfluoroethanesulfonic acid 
• 47374-41-4 1,1,2,2,2-Pentafluoro-ethanesulfonic acid (3-phenylsulfanyl-phenyl)-amide 
• 37950-57-5 1,1,2,2,2-Pentafluoro-ethanesulfonic acid (3-phenylsulfanyl-phenyl)-amide; compound with triethyl-amine 
• 2837-92-5 potassium perfluoroethanesulfonate 
• 22737-05-9 3-benzoylperfluoroethanesulfonanilide 
• 57728-78-6 4-Methylthiophenyl-perfluorethansulfonat 
• 57728-77-5 3-Methyl-4-methylthiophenyl-perfluorethansulfonat 
• 2923-21-9 perfluoroethanesulfonate sodium salt 
• 6226-26-2 1,1,2,2,2-Pentafluoro-ethanesulfonic acid 2,2,2-trifluoro-ethyl ester 
• 23588-89-8 triethylamine hydrofluoride 
• 7789-23-3 potassium fluoride 

Relevant academic research and scientific papers

Perfluoroethanesulfonyl fluoride: Preparation from sultone

A procedure was developed for preparing perfluoroethanesulfonyl fluoride by synthesis of hexafluoropropane-2-β-sultone from sulfuric anhydride and perfluoropropene, followed by hydrolysis of the sultone to α- tetrafluoroethanesulfonyl fluoride and fluorination of the latter with elemental fluorine.

Die elektrochemische fluorierung von alkansulfonamiden und alkandisulfonamiden

Alkane sulphonylamides and disulphonylamides are stable in anhydrous (HF)x and undergo quantitative fission of S-N bonds during electrochemical fluorination. Besides NF3, the corresponding perfluoroalkane sulphonyl fluorides and disulphonyl fluorides are formed.

SYNTHESIS OF PERFLUOROPROPANE-1,3-DISULFONIC ACID AND PERFLUOROBUTANE-1,4-DISULFONIC ACID

Perfluoropropane-1,3-disulfonic acid, HO3S-(CF2)3-SO3H, and perfluorobutane-1,4-disulfonic acid, HO3S-(CF2)4-SO3H, have been prepared electrochemically from the alkanedisulfonyl difluorides.Whereas perfluoroalkanemonosulfonyl fluorides can easily be prepared via electrochemical fluorination the situation with disulfonyl difluorides is somewhat more difficult.NMR data are reported for all compounds.

DIE ELEKTROFLUORIERUNG VON Α-CHLORETHYLSULFOCHLORID

The electrochemical fluorination of CH3CHClSO2Cl was studied at different conditions.Besides methane- and ethane-derivates, SO2F2 and SF6, the products formed are the two sulfonylfluorides C2F5SO2F and CF3CFClSO2F.The yield of CF3CFClSO2F was greater at l