35427-68-0

Basic information

• Product Name: 1-chloro-N,N-dimethylmethanesulfonamide(SALTDATA: FREE)
• Synonyms: 1-chloro-N,N-dimethylmethanesulfonamide(SALTDATA: FREE);1-chloro-N,N-dimethylmethanesulfonamide;1-chloro-N,N-dimethyl-methanesulfonamide;MFCD03085928
• CAS NO: 35427-68-0
• Molecular Formula: C₃H₈ClNO₂S
• Molecular Weight: 157.62
• Mol File: 35427-68-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-chloro-N,N-dimethylmethanesulfonamide(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: 1-chloro-N,N-dimethylmethanesulfonamide(SALTDATA: FREE)(35427-68-0)
• EPA Substance Registry System: 1-chloro-N,N-dimethylmethanesulfonamide(SALTDATA: FREE)(35427-68-0)

Safety Data

• Hazardous Substances Data: 35427-68-0(Hazardous Substances Data)

Usage

Salt Data

FREE

Usage

Reagent in organic synthesis

Application

Preparation of sulfonamide derivatives

Physical State

Colorless liquid

Odor

Strong, pungent

Chemical Reactions

Undergoes a range of chemical reactions

Industries

Used in pharmaceuticals, agriculture, and materials science

Source

Effective source of chloroalkylating agents

Reactivity

High reactivity with nucleophiles

Safety Precautions

Handle with caution

Health Risk

Hazardous to human health

Environmental Risk

Hazardous to the environment

Ventilation

Should be used in well-ventilated areas

Safety Measures

Appropriate safety measures should be taken during handling

Upstream product

• 3518-65-8 monochloromethanesulfonyl chloride 
• 124-40-3 dimethyl amine 

Downstream Products

• 861640-78-0 (3-([(dimethylamino)sulfonyl]methyl)-2-nitro-5,10,15,20-tetraphenylporphyrinato)zinc(II) 
• 473530-12-0 N,N-dimethyl-C-(5-phenyl-1,2,4-triazine)-methanesulphonamide 
• 130008-15-0 1,2-bis(N,N-dimethylsulfamoyl)-1,1a,1b,2-tetrahydro-1a-phenylbisazirino<1,2-a:2',1'-c>quinoxaline 
• 110380-88-6 (2R,3R)-3-Phenyl-oxirane-2-sulfonic acid dimethylamide 

Relevant articles and documents

Process for producing piperazinesulfonamide derivatives and salts thereof

A process for advantageously preparing a piperazinesulfonamide derivative represented by the general formula (III): wherein R1 is hydrogen atom, a straight or branched chain alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a halogen atom, hydroxyl group, trifluoromethyl group, nitro group or amino group; R2 is a phenyl group which may have as substituents on its phenyl ring 1 to 3 groups selected from the group consisting of an alkyl group having 1 to 4 carbon atoms, an alkoxy group having 1 to 4 carbon atoms, a halogen atom, hydroxyl group, trifluoromethyl group, nitro group and amino group, 2-pyridyl group, 3-pyridyl group or 4-pyridyl group; each of R3 and R4 is independently hydrogen atom, a straight or branched chain alkyl group having 1 to 6 carbon atoms, a hydroxyalkyl group having 1 to 4 carbon atoms, a cycloalkyl group having 3 to 8 carbon atoms, or a phenyl group which may be substituted; and Y is an alkylene group having 1 to 12 carbon atoms, and a salt thereof.