355-49-7

Usage

Uses

Used in Cosmetics and Skincare Industry:
Perfluorohexadecane is used as an emollient and skin conditioning agent for its ability to form a smooth, protective film on the skin, enhancing the texture and appearance of the skin.
Used in Pharmaceutical Industry:
Perfluorohexadecane is used as a vehicle for drug delivery due to its ability to encapsulate and transport pharmaceutical agents, potentially improving the efficacy and safety of drug administration.
Used in Biomedical Industry:
In the biomedical field, perfluorohexadecane is utilized as a contrast agent for medical imaging, providing clear visualization of internal structures during diagnostic procedures.
Used in Oil and Gas Extraction:
Perfluorohexadecane is investigated for its potential use in oil and gas extraction, where its non-flammable and chemically inert properties can offer safety and efficiency benefits in the extraction process.
Used in Industrial and Consumer Products:
Its unique properties also make perfluorohexadecane suitable for use in various industrial and consumer products, where its non-conductive and chemically inert nature can be advantageous for specific applications.

InChI:InChI=1/C16F34/c17-1(18,3(21,22)5(25,26)7(29,30)9(33,34)11(37,38)13(41,42)15(45,46)47)2(19,20)4(23,24)6(27,28)8(31,32)10(35,36)12(39,40)14(43,44)16(48,49)50

Upstream product

• 544-76-3 Hexadecane 
• 96-49-1 [1,3]-dioxolan-2-one 
• 507-63-1 1-iodoheptadecafluorooctane 
• 87489-49-4 C₆F₁₃IZn 
• 335-65-9 hydroperfluorooctane 
• 355-43-1 n-perfluorohexyl iodide 
• 105-58-8 Diethyl carbonate 
• 3829-39-8 bis(perfluorooctyl)-diazene 
• 71-43-2 benzene 
• 287-92-3 Cyclopentane 
• 110-82-7 cyclohexane 
• 291-64-5 cycloheptane 
• 375-95-1 perfluorononanoic acid 
• 3829-39-8 Perfluorazooctan 

Downstream Products

• 116-14-3 polytetrafluoroethylene 
• 116-15-4 perfluoropropylene 
• 115-25-3 Octafluorocyclobutane 
• 357-26-6 octafluoro-1-butene 

Relevant academic research and scientific papers

Photolysis of Perfluoroazooctane in Perfluorohexane upon 185 nm Irradiation

The photolysis of perfluoroazooctane in perfluorohexane upon 185 nm irradiation was investigated by means of quantum yield, light intensity dependence, and UV-vis spectra of the photolysis of perfluoroazooctane.Perfluoroazooctane (trans isomer) was photoi

Perfluorooctylation of aromatic compounds with perfluoroazooctane upon 185 nm irradiation in a two-phase system

An efficient method for the preparation of perfluorooctylated aromatic and heteroaromatic compounds has been developed using photolysis of perfluoroazooctane (E)-1 upon 185 nm irradiation. The use of a two-phase system made up of a perfluorohexane solution of (E)-1 and a suitable aromatic compound has proved efficient for this reaction. The photolytic mechanism of (E)-1 upon 185 nm irradiation has also been investigated on the basis of quantum yield, light intensity dependence and UV-VIS spectra. It is shown that (E)-1 is photoisomerized by one photon absorption to the (Z)-isomer, with subsequent extrusion of nitrogen by a second photon absorption.

A Direct Introduction of Perfluorooctyl Group into Cycloalkanes using the Photolysis of Perfluoroazooctane upon 185 nm Irradiation

Perfluorooctyl-substituted cycloalkanes are prepared directly by photolysis of perfluoroazooctane in cycloalkanes upon 185 nm irradiation; a plausible mechanism is discussed on the basis of the time-course, quantum yield, and light intensity dependence during this photoreaction.

METHOD FOR PRODUCING TETRAFLUOROETHYLENE AND/OR HEXAFLUOROPROPYLENE

PROBLEM TO BE SOLVED: To provide a novel method for producing tetrafluoroethylene and/or hexafluoropropylene. SOLUTION: The method for producing tetrafluoroethylene and/or hexafluoropropylene comprises thermally decomposing a perfluoroalkane represented by the general formula (1) defined by CnF2n+2, where n represents an integer of 4-28.] COPYRIGHT: (C)2016,JPOandINPIT

An improved procedure for the synthesis of perfluoroalkylacetylenes

A new and easy way to synthesize acetylene compounds is proposed. This synthesis is improved by including in one-pot, three reactions in a single step, with good yields. The reactants are commonly used compounds.

Reaction of Perfluoroalkyl Iodides with Lithium Salt of 5-Nitro-3-tert-butyl-1,3-tetrahydrooxazine

Reaction of perfluoroalkyl iodides C6F13I and C8H17I with lithium salt of 5-nitro-3-tert-butyl-1,3-tetrahydrooxazine in DMSO at 20°C for 24 h in an argon atmosphere gives 5-nitro-5-perfluoroalkyl-3-tert-butyl-1,3-tetrahydrooxazines (yield 66-75%), 5,5′-bis(5-nitro-3-tert-butyltetrahydro-1,3-oxazinyl) (yield 3-5%), and, respectively, perfluorododecane and perfluorohexadecane. The reaction is accelerated under UV irradiation.

Electroorganic synthesis 65. Anodic homocoupling of carboxylic acids derived from fatty acids

Fatty acid derived carboxylic acids with double bonds, hydroxy-, amino-, keto-, ester- and epoxy groups are anodically coupled to dimers (Kolbe electrolysis) in 29 to 81% yield and up to a 2.5 mol scale. Problems due to the low conductivity of fatty acid salts were overcome by the use of a flow cell with a narrow electrode gap. Fatty acids with branched alkyl chains gave dimers with interesting emulsifying properties. Dimethyl hexadecanedioate, accessible from methyl azelate, could be cyclized and further converted into homomuscone and muscone in a few steps. A commercial mixture of dimeric fatty acids (C36-dicarboxylic acids) has been coupled to give C70-diesters. Acta Chemica Scandinavica 1998. Part 64: Nielsen, M. F., Batanero, B.,.

Perfluoroalkylation of Benzene by 185 nm Photolysis of Perfluoroazooctane

Perfluoroazooctane was photolyzed in benzene upon low pressure Hg lamp irradiation to generate perfluorooctyl radicals, which reacted with an excess of benzene to afford perfluorooctylbenzene.The investigation on the wavelength and light intensity dependence revealed that this photolysis proceeded effectively upon 185 nm irradiation by two photon absorption.

Solvent effects on the reaction of perfluoroalkyl iododes and α,ω-perfluoroalkyl diiodides with cadmium powder and dimethylcadmium

Reaction of RfI (Rf=C6F13 or C8F17) with Cd powder in DMF at room temperature under N2 afforded RfCdX (X=I or Rf) in moderate (48-52percent) yield.Although no reaction was observed with Cd powder and RfI (Rf=C6F13 or C8F17) in CH3CN at room temperature, reaction at reflux gave the homocoupled products C6F13-C6F13 (67percent) and C8F17-C8F17 (61percent) respectively.No F-alkylcadmium reagent was detected by 19F NMR spectroscopy.Similarly, the reaction of I(CF2)nI (n=3, 4) with Cd powder in DMF and CH3CN was examined.In DMF at room temperature, the new dicadmium reagents ICd(CF2)nCdI and ICd(CF2)2nCdI (60-65percent combined yield) were formed.No reaction was observed with Cd powder and I(CF2)nI (n=3, 4, 6) in CH3CN at room temperature, but at reflux a mixture of higher α,ω-diiodoperfluoroalkanes, i.e.I(CF2)2nI, I(CF2)3nI, I(CF2)4nI, I(CF2)5nI, resulted.Treatment of I(CF2)nI (n=3, 4) with CdMe2 (1:2) in CH3CN afforded the new ω-iodo F-alkylcadmium reagents, 2Cd*(CH3CN), in 96percent (n=3) and 57percent (n=4) yields.Reaction of Me2Cd with either ICF2CF2I or BrCF2CF2I in CH3CN or HMPA at 0 deg C resulted in tetrafluoroethylene only.