355-49-7

Basic information

• Product Name: PERFLUOROHEXADECANE
• Synonyms: Hexadecane, tetratriacontafluoro-;perfluoro-N-hexadecane;tetratriacontafluorohexadecane;PERFLUOROHEXADECANE;Perfluorinated paraffins;Perfluorohexadecane 97%;Perfluorohexadecane97%
• CAS NO: 355-49-7
• Molecular Formula: C₁₆F₃₄
• Molecular Weight: 838.12
• EINECS: 206-588-7
• Mol File: 355-49-7.mol
• Article Data: 17

Chemical Properties

• Melting Point: 125-126°C
• Boiling Point: 239-240°C
• Flash Point: 113.8 °C
• Appearance: /
• Density: 1.9000 (rough estimate)
• Vapor Pressure: 0.0179mmHg at 25°C
• Refractive Index: 1.2830 (estimate)
• CAS DataBase Reference: PERFLUOROHEXADECANE(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUOROHEXADECANE(355-49-7)
• EPA Substance Registry System: PERFLUOROHEXADECANE(355-49-7)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 355-49-7(Hazardous Substances Data)

Usage

General Description

Perfluorohexadecane is a fluorocarbon compound with the chemical formula C16F34. It is a colorless, odorless liquid that is insoluble in water and has a low toxicity. Perfluorohexadecane is commonly used in cosmetics and skincare products as an emollient and skin conditioning agent due to its ability to form a smooth, protective film on the skin. It also has potential applications in the pharmaceutical and biomedical industries, particularly as a vehicle for drug delivery and as a contrast agent for medical imaging. Additionally, perfluorohexadecane has been investigated for its potential use in oil and gas extraction, as well as in industrial and consumer products for its unique properties as a non-flammable, non-conductive, and chemically inert substance.

InChI:InChI=1/C16F34/c17-1(18,3(21,22)5(25,26)7(29,30)9(33,34)11(37,38)13(41,42)15(45,46)47)2(19,20)4(23,24)6(27,28)8(31,32)10(35,36)12(39,40)14(43,44)16(48,49)50

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 507-63-1 1-iodoheptadecafluorooctane 
• 87489-49-4 C₆F₁₃IZn 
• 3829-39-8 bis(perfluorooctyl)-diazene 
• 71-43-2 benzene 
• 3829-39-8 Perfluorazooctan 
• 544-76-3 Hexadecane 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 107-18-6 allyl alcohol 
• 307-35-7 perfluorooctyl sulfofluorure 
• 375-95-1 perfluorononanoic acid 
• 291-64-5 cycloheptane 
• 110-82-7 cyclohexane 
• 287-92-3 Cyclopentane 

Downstream Products

• 116-14-3 polytetrafluoroethylene 
• 116-15-4 perfluoropropylene 
• 115-25-3 Octafluorocyclobutane 
• 357-26-6 octafluoro-1-butene 

Relevant articles and documents

Photolysis of Perfluoroazooctane in Perfluorohexane upon 185 nm Irradiation

The photolysis of perfluoroazooctane in perfluorohexane upon 185 nm irradiation was investigated by means of quantum yield, light intensity dependence, and UV-vis spectra of the photolysis of perfluoroazooctane.Perfluoroazooctane (trans isomer) was photoi

A Direct Introduction of Perfluorooctyl Group into Cycloalkanes using the Photolysis of Perfluoroazooctane upon 185 nm Irradiation

Perfluorooctyl-substituted cycloalkanes are prepared directly by photolysis of perfluoroazooctane in cycloalkanes upon 185 nm irradiation; a plausible mechanism is discussed on the basis of the time-course, quantum yield, and light intensity dependence during this photoreaction.

An improved procedure for the synthesis of perfluoroalkylacetylenes

A new and easy way to synthesize acetylene compounds is proposed. This synthesis is improved by including in one-pot, three reactions in a single step, with good yields. The reactants are commonly used compounds.

Reaction of Perfluoroalkyl Iodides with Lithium Salt of 5-Nitro-3-tert-butyl-1,3-tetrahydrooxazine

Reaction of perfluoroalkyl iodides C6F13I and C8H17I with lithium salt of 5-nitro-3-tert-butyl-1,3-tetrahydrooxazine in DMSO at 20°C for 24 h in an argon atmosphere gives 5-nitro-5-perfluoroalkyl-3-tert-butyl-1,3-tetrahydrooxazines (yield 66-75%), 5,5′-bis(5-nitro-3-tert-butyltetrahydro-1,3-oxazinyl) (yield 3-5%), and, respectively, perfluorododecane and perfluorohexadecane. The reaction is accelerated under UV irradiation.