375-95-1

Basic information

• Product Name: PERFLUORONONANOIC ACID
• Synonyms: HEPTADECAFLUORO-N-NONANOIC ACID;HEPTADECAFLUORONONANOIC ACID;HEPTADECAFLUOROPELARGONIC ACID;PFNA;PERFLUORONONANOIC ACID;PERFLUORO-N-NONANOIC ACID;PERFLUOROPELARGONIC ACID;N-HEPTADECAFLUORONONANOIC ACID
• CAS NO: 375-95-1
• Molecular Formula: C₉HF₁₇O₂
• Molecular Weight: 464.08
• EINECS: 206-801-3
• Product Categories: Fluorous Chemistry;Fluorous Compounds;Synthetic Organic Chemistry
• Mol File: 375-95-1.mol
• Article Data: 8

Chemical Properties

• Melting Point: 59-62 °C(lit.)
• Boiling Point: 218°C
• Flash Point: 218°C
• Appearance: white crystalline powder
• Density: 1.7397 (estimate)
• Vapor Pressure: 0.171mmHg at 25°C
• Refractive Index: 1.288
• Storage Temp.: Refrigerator
• Solubility: Acetone (Slightly), DMSO (Slightly), Methanol (Slightly)
• PKA: 0.52±0.10(Predicted)
• Stability: Stable. Incompatible with strong bases, strong oxidizing agents. Corrosive - causes burns.
• BRN: 1897287
• CAS DataBase Reference: PERFLUORONONANOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: PERFLUORONONANOIC ACID(375-95-1)
• EPA Substance Registry System: PERFLUORONONANOIC ACID(375-95-1)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: UN3261
• WGK Germany: 3
• TSCA: Yes
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 375-95-1(Hazardous Substances Data)

Usage

Chemical Properties

Perfluorononanoic acid is a white crystalline powder or beige crystals. Perfluorononanoic acid has the ability to react with bases, oxidizing agents, and reducing agents. Upon decomposition, PFNA can form carbon oxides and hydrogen fluoride.

Uses

Different sources of media describe the Uses of 375-95-1 differently. You can refer to the following data:
1. Perfluorinated compounds (PFCs) are persistent in environments due to the high energy of C-F bond routes. PFNA may interfere in a toxic fashion on the immune system, liver, development, and endocrine systems.
2. Perfluorinated compounds (PFCs) are persistent in environments due to the high energy of C-F bond. Being a persistent environmental pollutant, it can accumulate in human tissues via various exposure routes. PFNA may interfere in a toxic fashion on the immune system, liver, development, and endocrine systems.

Definition

ChEBI: A fluoroalkanoic acid that is nonanoic acid in which all of the hydrogens in the alkyl chain are replaced by fluorines.

InChI:InChI=1/C9HF17O2/c10-2(11,1(27)28)3(12,13)4(14,15)5(16,17)6(18,19)7(20,21)8(22,23)9(24,25)26/h(H,27,28)

Upstream product

• 96-49-1 [1,3]-dioxolan-2-one 
• 507-63-1 1-iodoheptadecafluorooctane 
• 30377-52-7 perfluorononanoic acid ethyl ester 
• 124-38-9 carbon dioxide 
• 51300-88-0 (perfluoro n-octyl) magnesiumbromide 
• 79754-26-0 perfluorononanoyl peroxide 
• 21652-58-4 1H,1H,2H-perfluorodecene 

Downstream Products

• 423-56-3 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluorononanol 
• 88950-97-4 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-Heptadecafluoro-1-p-tolyl-nonan-1-one 
• 88950-95-2 4-Nonadecafluorononyl-benzoic acid 
• 307-33-5 1-Chloroperfluorooctane 
• 52447-23-1 heptadecafluorononanic acid chloride 
• 355-49-7 perfluorocetane 
• 117293-63-7 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluoro-N-[4-(1H-tetrazol-5-ylmethyl)phenyl]nonanamide 
• 375-85-9 perfluoroheptanoic acid 
• 335-67-1 Perfluorooctanoic acid 
• 124-38-9 carbon dioxide 
• 1435951-95-3 2-(4-methylcyclohex-3-en-1-yl)propan-2-yl heptadecafluorononanoate 
• 138901-05-0 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluoro-N-(phenylmethyl)-N-<4-(1H-tetrazol-5-ylmethyl)phenyl>nonanamide 
• 138901-47-0 perfluoro-N-(phenylmethyl)-N-<4-(cyanomethyl)phenyl>nonanamide 
• 117293-73-9 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,9-heptadecafluoro-N-<(4-cyanomethyl)phenyl>nonanamide 

Relevant articles and documents

Preparation method of fluorine-containing carboxylic acid

The invention discloses a preparation method of fluorine-containing carboxylic acid. The method comprises the following steps: reacting fluorine-containing carboxylate used as a raw material with an acylating chlorination reagent to obtain a corresponding mixture of fluorine-containing acyl chloride and fluorine-containing anhydride, and hydrolyzing and drying the mixture of fluorine-containing acyl chloride and fluorine-containing anhydride to obtain high-purity fluorine-containing carboxylic acid. The method provided by the invention is suitable for post-treatment of fluorine-containing carboxylic acid prepared by a fluorine-containing olefin (monoolefine, diene, cycloolefin and the like) oxidation method, replaces the traditional strong acid acidification and ether continuous extractionprocess, and is simpler, more convenient and more applicable; and the method can also be used for recovering and purifying a fluorine-containing carboxylate emulsifier. The purity of the fluorine-containing carboxylic acid prepared by the method can reach 98% or above.

Dimanganheptoxid zur selektiven Oxidation organischer Substrate

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REACTIVITE DES PERFLUOROIODOALCANES AVEC LES CARBONATES ET PYROCARBONATES D'ALCOYLES EN PRESENCE DE COUPLE METALLIQUE ZINC-CUIVRE

Perpluoroalkyl iodides RFI, in dissociating solvents, in the presence of zinc-copper couple give perfluoroorganic compounds RFZnI, which reac with alkyl carbonates and pyrocarbonates to give perfluorocarboxylic acids and perfluorocarboxylis esters of industrial interest.