35512-29-9

Basic information

• Product Name: 4-(4-CHLOROPHENYL)-1H-IMIDAZOLE
• Synonyms: 1-Chloro-4-(1H-imidazol-4-yl)benzene;4-(4-Chlorophenyl)-1H-imidazole 97%;4-(4-CHLOROPHENYL)-1H-IMIDAZOLE;5-(4-Chlorophenyl)-3H-imidazole;4-(1H-Imidazol-4-yl)chlorobenzene
• CAS NO: 35512-29-9
• Molecular Formula: C₉H₇ClN₂
• Molecular Weight: 178.61828
• Product Categories: Chemical Synthesis;Heterocyclic Building Blocks;Imidazoles;Heterocyclic Compounds;Building Blocks
• Mol File: 35512-29-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 136-142 °C
• Boiling Point: 404.7 °C at 760 mmHg
• Flash Point: 230.9 °C
• Appearance: /
• CAS DataBase Reference: 4-(4-CHLOROPHENYL)-1H-IMIDAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-CHLOROPHENYL)-1H-IMIDAZOLE(35512-29-9)
• EPA Substance Registry System: 4-(4-CHLOROPHENYL)-1H-IMIDAZOLE(35512-29-9)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 35512-29-9(Hazardous Substances Data)

Usage

General Description

4-(4-Chlorophenyl)-1H-imidazole is a chemical compound with the molecular formula C9H7ClN2. It is an imidazole derivative and contains a chlorophenyl group as a substituent. This chemical has various applications, including as an intermediate in the synthesis of pharmaceuticals, pesticides, and other organic compounds. It is also used in research and development for its potential biological and pharmacological properties. Additionally, 4-(4-Chlorophenyl)-1H-imidazole may have antimicrobial and antifungal properties, making it a potential candidate for the development of new medical treatments. It is important to handle and use this chemical with caution due to its potential health hazards and environmental impact.

Upstream product

• 89108-47-4 4-diazo-4H-imidazole 
• 108-90-7 chlorobenzene 
• 2302-25-2 4-bromo-1 H-imidazole 
• 1679-18-1 4-Chlorophenylboronic acid 
• 50-00-0 formaldehyd 
• 27993-56-2 1-(4-chlorophenyl)-2-hydroxyethanone 
• 93103-18-5 4-(4-chloro-phenyl)-1,3-dihydro-imidazole-2-thione 
• 873-73-4 4-n-chlorophenylacetylene 
• 5467-71-0 4-chlorophenacylamine hydrochloride 
• 77287-34-4 formamide 
• 536-38-9 4-chlorobenzoylmethyl bromide 

Relevant articles and documents

Enantioselective γ-Addition of Pyrazole and Imidazole Heterocycles to Allenoates Catalyzed by Chiral Phosphine

Chiral phosphines were found to catalyze the enantioselective asymmetric γ-addition of heteroaromatic compounds to allenoates in good yields with high enantiomeric ratios and regioselectivity in the presence of (S)-BINOL. Both pyrazole and imidazole could

One-pot synthesis of 2-alkyl-4(5)-aryl-1H-imidazoles from 1-aryl-2-bromoethanones, ammonium carbonate and aliphatic carboxylic acids

A simple and efficient protocol for the preparation of 2-alkyl-4(5)-aryl- 1H-imidazoles starting from α-bromo aryl methyl ketones and aliphatic carboxylic acids in the presence of ammonium carbonate has been developed.

Imidazolylpyrimidine based CXCR2 chemokine receptor antagonists

An imidazolylpyrimidine was identified in a CXCR2 chemokine receptor antagonist screen and was optimized for potency, in vitro metabolic stability, and oral bioavailability. It was found that subtle structural modification within the series affected the o