3553-78-4

Basic information

• Product Name: Butylthiotrimethylsilane
• Synonyms: (Butylthio)trimethylsilane;Butylthiotrimethylsilane
• CAS NO: 3553-78-4
• Molecular Formula: C₇H₁₈SSi
• Molecular Weight: 162.37
• Mol File: 3553-78-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 75.5-78 °C(Press: 40 Torr)
• Appearance: /
• Density: 0.8390 g/cm3(Temp: 27 °C)
• CAS DataBase Reference: Butylthiotrimethylsilane(CAS DataBase Reference)
• NIST Chemistry Reference: Butylthiotrimethylsilane(3553-78-4)
• EPA Substance Registry System: Butylthiotrimethylsilane(3553-78-4)

Safety Data

• Hazardous Substances Data: 3553-78-4(Hazardous Substances Data)

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 109-79-5 n-butanethiol 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 479486-96-9 N,N-dimethyl (trimethylsilyl)methanamide 
• 7677-24-9 trimethylsilyl cyanide 
• 32812-85-4 {Pb(C₄H₉S)2} 
• 55274-10-7 dibutyl(trimethylsilyl) phosphite 

Downstream Products

• 7133-40-6 cyclohexyl n-butyl sulfide 
• 1825-61-2 Trimethylmethoxysilane 
• 6306-17-8 butyl phenacyl sulfide 
• 1486-38-0 S-butyldiphenylthiophosphinite 
• 15318-33-9 chlorocarbonylbis(triphenylphosphine)rhodium(I) 
• 16029-98-4 trimethylsilyl iodide 
• 150-50-5 merphos 

Relevant articles and documents

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Synthesis and characterization of 2-carboxyethyltriphenyl phosphonium tribromide and its application as catalyst in silylation of alcohols and thiols under solvent-free condition

A phosphonium-based catalyst, 2-carboxyethyltriphenyl phosphonium tribromide (CTPTB), has been synthesized by reacting triphenyl phosphine with acrylic acid and potassium bromide under solvent-free condition followed by oxidation of Br- to with KMnO4. This hitherto unknown tribromide reagent is characterized by ultraviolet-visible, Fourier transform-infrared, 1H NMR, and 31P NMR spectroscopy. Its efficacy as catalyst is established by investigating its catalytic activity in silylation of alcohols and thiols by hexamethyl disilazane (HMDS). It is found to be a very good catalyst and selectively and efficiently catalyzes the silylation reactions. Copyright

Efficient Preparation of a Key Intermediate in the Synthesis of Roxifiban by Enzymatic Dynamic Kinetic Resolution on Large Scale

Additional information is presented for the transformation of a kinetic resolution into a dynamic kinetic resolution of the isobutyl ester 5b to form the acid 2 in high yield and ee via the intermediacy of a thioester 6c, (Pesti, J. A.; Yin, J.; Zhang, L.-H; Anzalone, L. J. Am. Chem. Soc. 2001, 123, 11075-11076.). The development of optimized reaction conditions for the preparation of 6c, its dynamic kinetic resolution to 2, and the scale-up of both reactions into a pilot plant are described.