3557-70-8

Usage

Uses

Used in Organic Synthesis:
2-(4-Bromophenyl)-4,6-diphenylpyridine is used as a key intermediate in organic synthesis for the preparation of various complex organic molecules. Its unique structure and reactivity make it a versatile building block for the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 2-(4-Bromophenyl)-4,6-diphenylpyridine is used as a starting material for the development of new drugs. Its biological activities and structural features make it a promising candidate for the design and synthesis of novel therapeutic agents targeting various diseases.
Used in Medicinal Chemistry:
2-(4-Bromophenyl)-4,6-diphenylpyridine is utilized as a valuable component in medicinal chemistry for the exploration of new chemical entities with potential therapeutic applications. The bromine substitution on the phenyl group offers unique reactivity, enabling the synthesis of diverse bioactive compounds with improved pharmacological properties.

InChI:InChI=1/C23H16BrN/c24-21-13-11-19(12-14-21)23-16-20(17-7-3-1-4-8-17)15-22(25-23)18-9-5-2-6-10-18/h1-16H

Upstream product

• 24358-62-1 1-(4-bromophenyl)ethylamine 
• 7338-94-5 1,3-diphenyl-2-propynone 
• 618-36-0 rac-methylbenzylamine 
• 39833-48-2 3-(4-bromophenyl)-1-phenylprop-2-yn-1-one 
• 299456-72-7 1-(4-bromophenyl)ethanone O-acetyl oxime 
• 358621-92-8 N-(p-tolylsulfonyl)-1,3-diphenyl-2-propen-1-imine 
• 99-90-1 para-bromoacetophenone 
• 76570-24-6 2-chloro-4 ,6-diphenylpyridine 
• 5467-74-3 4-Bromophenylboronic acid 
• 2403-27-2 1-(4-bromophenyl)-3-phenyl-2-propen-1-one 
• 16883-69-5 N-phenacylpyridinium bromide 
• 2218-15-7 1-phenyl-2-(pyrrolidin-1-yl)ethanone 
• 94-41-7 benzalacetophenone 
• 614-47-1 1,3-diphenyl-propen-3-one 

Downstream Products

• 1346669-25-7 C₄₇H₃₀N₂S 
• 1346669-37-1 C₅₉H₃₉N₃ 

Relevant academic research and scientific papers

A novel and efficient 2,4,6-trisubstituted pyridine ring synthesis via α-benzotriazolyl ketones

Reaction of α-benzotriazolyl ketones with α,β-unsaturated ketones resulted in 2,4,6-triarylpyridines, 2,4-diaryl-5H-indeno[1,2-b]pyridines and 2,4-diaryl-5,6-dihydrobenzo[h]quinolines in good yields.

Regiocontrolled synthesis of 2,4,6-triarylpyridines from methyl ketones, electron-deficient acetylenes and ammonium acetate

A novel one-pot two-step approach for the synthesis of 2,4,6-triarylpyridinesvia t-BuOK/DMSO-promotedC-vinylation of a variety of methyl ketones with electron-deficient acetylenes (alkynones) followed by a cyclization of thein situgenerated unsaturated 1,5-dicarbonyl species with ammonium acetate has been developed. This approach possesses competitive advantages such as high regioselectivity, available starting materials and the absence of transition-metal catalysts, oxidants and undesirable byproducts. A wide synthetic utility of the developed approach was demonstrated by the synthesis of trisubstituted, tetrasubstituted and fused pyridines.

Compound, photoelectric conversion device, and electronic device

The invention provides a compound shown as a formula I, a photoelectric conversion device and an electronic device, and belongs to the technical field of organic materials. The compound can reduce theworking voltage of the photoelectric conversion device, improve the luminous efficiency of the photoelectric conversion device and prolong the service life of the device.

Synthesis of Highly Substituted Pyridines through Copper-Catalyzed Condensation of Oximes and α,β-Unsaturated Imines

A copper-catalyzed condensation reaction of oxime acetates and α,β-unsaturated ketimines to give pyridine derivatives is reported. The reaction features mild conditions, high functional-group compatibility, and high regioselectivity with respect to unsymmetrical oxime acetates, thus allowing the preparation of a wide range of polysubstituted pyridines, many of which are not readily accessible by conventional condensation methods.

Heterocyclic compound and organic light-emitting device including the same

A heterocyclic compound represented by Formula 1 below and an organic light-emitting device including the heterocyclic compound are provided:

Base-Promoted β-C(sp3)-H Functionalization of Enaminones: An Approach to Polysubstituted Pyridines

A convenient one-pot base-promoted synthesis of polysubstituted pyridines from 1-arylethylamines and ynones through the direct β-C(sp3)-H functionalization of enaminones under metal-free conditions has been developed. An intermolecular Michael addition reaction and an intramolecular condensation were involved in this procedure, which features high regioselectivity, high efficiency, and environmental friendliness. Various polysubstituted pyridines were provided in up to 92% yield for 34 examples.

ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT

There are provided an organic having both excellent hole transporting property and satisfactory electron transporting and showing excellent durability against electric oxidation/reduction and a high triplet excitation level, and a charge transporting material and an organic electroluminescent device each using the organic compound. The organic compound is represented by following Formula (I): wherein Cz 1 and Cz 2 each represent a carbazolyl group; Z represents a direct bond or an arbitrary linkage group enabling the conjugation of nitrogen atoms in the carbazole rings of Cz 1 and Cz 2 with each other; and Q represents a direct bond connecting to "G" in following Formula (II): wherein Ring B 1 represents a six-membered aromatic heterocyclic ring having "n" nitrogen atom(s) as hetero atom(s); "n" represents an integer of from 1 to 3; G represents a direct bond or an arbitrary linkage group connecting to Q when G connects to Q; Gs connect to carbon atoms at the ortho-position and the para-position with respect to nitrogen atom(s) in Ring B 1 ; G represents an aromatic hydrocarbon group when G does not connect to Q; and "m" represents an integer of from 3 to 5.

Microwave-promoted and Lewis acid catalysed synthesis of 2,4,6-triarylpyridines using urea as benign source of ammonia

An efficient method for the synthesis of 2,4,6-triarylpyridines via microwave-promoted and BF3·OEt2-catalysed one-pot reaction of ω-pyrrolidinoacetophenone with chalcone is reported. This method illustrates urea as an environmentally

Efficient synthesis of pyridines via a sequential solventless aldol condensation and Michael addition

The synthesis of pyridines was conducted by using a sequential solventless aldol condensation and Michael addition. The conventional synthesis of enones from a benzaldehyde and an aryl ketone involved the synthesis of the enolate by solubilizing the ketone in a basic alcohol solution. The result showed that the aldol condensation of an enolisable ketone and a benzaldehyde followed by Michael addition of the enone with a second enolisable ketone under solvent free conditions lead to the quantitative formation of diketone.

Pyrylium Compounds. XXI. - Structure and Tautomerism of Pseudobases of Unsymmetrically Substituted 2,4,6-Triarylpyrylium Salts

Hydrolytic ring opening of unsymmetrically substituted 2,4,6-triarylpyrylium salts 11 results in a mixture of two tautomeric pseudobases, the penten-1,5-diones 13 and 14.In crystalline state as a rule one of these tautomers markedly predominates, whereas