35582-07-1

Basic information

• Product Name: 2-(3-nitrophenyl)Oxazole
• Synonyms: 2-(3-nitrophenyl)Oxazole
• CAS NO: 35582-07-1
• Molecular Formula: C₉H₆N₂O₃
• Molecular Weight: 190.15554
• Mol File: 35582-07-1.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3-nitrophenyl)Oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3-nitrophenyl)Oxazole(35582-07-1)
• EPA Substance Registry System: 2-(3-nitrophenyl)Oxazole(35582-07-1)

Safety Data

• Hazardous Substances Data: 35582-07-1(Hazardous Substances Data)

Usage

Type of compound

oxazole (five-membered aromatic ring with one oxygen and one nitrogen atom)

Nitro group attachment

at the 3-position of the phenyl ring

Usage

in organic synthesis and medicinal chemistry as a building block for creating more complex molecules

Suitability

for certain reactions and applications in the research and development of pharmaceuticals and other organic compounds

Upstream product

• 88186-35-0 4,5-dihydro-2-(3-nitrophenyl)oxazole 
• 288-42-6 oxazol 
• 645-00-1 m-iodonitrobenzene 
• 121-92-6 3-nitrobenzoic acid 
• 93-89-0 benzoic acid ethyl ester 
• 18838-10-3 N-(2-hydroxyethyl)-benzamide 
• 7127-19-7 2-phenyl-1,3-oxazoline 
• 20662-88-8 2-phenyloxazole 

Downstream Products

• 35582-08-2 2-(3-aminophenyl)1,3-oxazole 

Relevant articles and documents

HEPARAN SULFATE BIOSYNTHESIS INHIBITORS FOR THE TREATMENT OF DISEASES

Described herein are compounds of Formula I, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or conditions in need of inhibition of heparan sulfate biosynthesis.

Regioselective functionalization of the oxazole scaffold using TMP-bases of Mg and Zn

A general method for the synthesis of 2,4,5-trisubstituted oxazoles has been developed. Starting from commercially available oxazole, successive metalations using TMPMgCl·LiCl or TMPZnCl·LiCl led to the corresponding magnesiated or zincated species which

SYNTHESIS AND SOME ELECTROPHILIC SUBSTITUTION REACTIONS OF 2-PHENYLOXAZOLE

A new synthesis of 2-phenyloxazole that includes the preparation of 2-phenyloxazoline and aromatization of the latter by the action of nickel peroxide was developed.It was established that under conditions that exclude protonation electrophilic substituti