35588-38-6

Basic information

• Product Name: 2-Chloro-N-(5-chloro-2-hydroxyphenyl)acetamide
• Synonyms: 2-Chloro-N-(5-chloro-2-hydroxyphenyl)acetamide
• CAS NO: 35588-38-6
• Molecular Formula: C₈H₇Cl₂NO₂
• Molecular Weight: 220.05268
• Mol File: 35588-38-6.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Chloro-N-(5-chloro-2-hydroxyphenyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Chloro-N-(5-chloro-2-hydroxyphenyl)acetamide(35588-38-6)
• EPA Substance Registry System: 2-Chloro-N-(5-chloro-2-hydroxyphenyl)acetamide(35588-38-6)

Safety Data

• Hazard Codes: Xi
• Statements: 41
• Safety Statements: 26-39
• HazardClass: IRRITANT
• Hazardous Substances Data: 35588-38-6(Hazardous Substances Data)

Upstream product

• 79-04-9 chloroacetyl chloride 
• 95-85-2 2-hydroxy-5-chloro-aniline 

Downstream Products

• 908863-01-4 2-chloro-N-(5-chloro-2-hydroxy-3-nitro-phenyl)-acetamide 
• 70558-11-1 6-chloro-3,4-dihydro-2H-benzo[b][1,4]oxazine 
• 63842-22-8 5-chloro-2-(chloromethyl)-1,3-benzoxazole 
• 52042-27-0 6-chloro-4-(2,3-dihydroxy-propyl)-4H-benzo[1,4]oxazin-3-one 
• 321126-82-3 8-amino-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 870064-73-6 6-chloro-8-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 7652-29-1 6-chloro-2H-1,4-benzoxazin-3(4H)-one 

Relevant articles and documents

COMPOUNDS HAVING PDE9A INHIBITORY ACTIVITY, AND PHARMACEUTICAL USES THEREOF

The present invention provides a compound having a specific chemical structure and having PDE9A inhibitory activity, or a pharmaceutically acceptable salt thereof. The present invention provides a composition containing the compound or a pharmaceutically acceptable salt thereof. The present invention provides a pharmaceutical use, for treating or preventing PDE9A-related diseases, of the compound according to the present invention, a salt thereof, and a composition containing the compound or salt. The present invention also provides a method for treating or preventing PDE9A-related diseases, the method comprising administering an effective amount of the compound according to the present invention, a salt thereof, or a composition containing the compound or salt to a subject in need of treatment.

FUNCTIONALLY SELECTIVE LIGANDS OF DOPAMINE D2 RECEPTORS

The present invention relates to novel functionally selective ligands of dopamine D2 receptors, including agonists, antagonists, and inverse agonists. The invention further relates to the use of these compounds for treating central nervous system disorders related to D2 receptors.

Pharmaceutical Compositions Comprising Nitrogen-Containing Fused Ring Coumpounds

[Problems] The present invention provides pharmaceutical composition which is effective for the prophylaxis or treatment of pathology showing involvement of uric acid (hyperuricemia, gouty tophus, acute gout arthritis, chronic gout arthritis, gouty kidney, urolithiasis, renal function disorder, coronary arterial disease, ischemic heart disease and the like) and the like, and is superior in the time-course stability and dissolution property (disintegration property). [Solving Means] The pharmaceutical composition of the present invention is a pharmaceutical composition comprising a nitrogen-containing fused ring compound represented by the following formula [1] or a pharmaceutically acceptable salt thereof, and one or more pharmaceutically acceptable additives, wherein the nitrogen-containing fused ring compound or a pharmaceutically acceptable salt thereof is not in contact with a basic additive: wherein each symbol is as described in the specification.