356068-84-3

Upstream product

• 90433-74-2 4-benzoyl-3,5-dimethyl-1H-pyrrole-2-carboxylic acid ethyl ester 
• 2199-44-2 3,5-dimethyl-2-ethoxycarbonyl-1H-pyrrole 
• 98-88-4 benzoyl chloride 

Downstream Products

• 24836-10-0 (2,4-dimethyl-1H-pyrrol-3-yl)(phenyl)methanone 

Relevant academic research and scientific papers

Combination therapy for the treatment of cancer

The present invention relates to methods for treatment or prevention of neoplasia disorders using protein tyrosine kinase inhibitors in combination with cyclooxygenase inhibitors, in particular cyclooxygenase-2 selective inhibitors.

Pyrrole substituted 2-indolinone protein kinase inhibitors

The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.