35621-01-3 Usage
General Description
4-Aminopiperidine dihydrochloride is a chemical compound that consists of a piperidine ring with an amino group attached to one of its carbon atoms, along with two hydrochloride ions. It is used in the synthesis of other organic compounds and as a reagent in chemical research. It has also been studied for its potential pharmacological effects, particularly in the field of neuroscience, where it has been investigated as a potential treatment for neurological disorders. 4-Aminopiperidine dihydrochloride is soluble in water, making it easy to handle and use in laboratory settings, and it has a range of chemical and biological applications due to its structure and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 35621-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,2 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35621-01:
(7*3)+(6*5)+(5*6)+(4*2)+(3*1)+(2*0)+(1*1)=93
93 % 10 = 3
So 35621-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2.2ClH/c6-5-1-3-7-4-2-5;;/h5,7H,1-4,6H2;2*1H
35621-01-3Relevant articles and documents
Solvent-freeN-Boc deprotection byex situgeneration of hydrogen chloride gas
De Borggraeve, Wim M.,Gilles, Philippe,Van Mileghem, Seger,Verschueren, Rik H.
supporting information, p. 5782 - 5787 (2021/07/12)
An efficient, scalable and sustainable method for the quantitative deprotection of thetert-butyl carbamate (N-Boc) protecting group is described, using down to near-stoichiometric amounts of hydrogen chloride gas in solvent-free conditions. We demonstrate theex situgeneration of hydrogen chloride gas from sodium chloride and sulfuric acid in a two-chamber reactor, introducing a straightforward method for controlled and stoichiometric release of HCl gas. The solvent-free conditions allow deprotection of a wide variety ofN-Boc derivatives to obtain the hydrochloride salts in quantitative yields. The procedure obviates the need for any work-up or purification steps providing an uncomplicated green alternative to standard methods. Due to the solvent-free, anhydrous conditions, this method shows high tolerance towards acid sensitive functional groups and furnishes expanded functional group orthogonality.
