35621-01-3 Usage
Uses
Used in Chemical Synthesis:
4-Aminopiperidine dihydrochloride is used as a building block in the synthesis of various organic compounds, leveraging its reactive amino and piperidine functionalities to form a wide array of chemical products.
Used in Chemical Research:
As a reagent, 4-Aminopiperidine dihydrochloride is employed in chemical research to explore its properties and reactions, contributing to the understanding of chemical mechanisms and the development of new methodologies.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 4-Aminopiperidine dihydrochloride is used as a starting material or intermediate in the development of new drugs, particularly those targeting neurological disorders, due to its potential pharmacological effects.
Used in Neuroscience Research:
4-Aminopiperidine dihydrochloride is utilized in neuroscience research as a subject of study for its potential as a treatment for neurological disorders, with investigations focusing on its interactions with the nervous system and its therapeutic possibilities.
These applications highlight the versatility of 4-Aminopiperidine dihydrochloride in both the chemical and pharmaceutical sectors, underscoring its importance in the synthesis of new compounds and the advancement of treatments for neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 35621-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,6,2 and 1 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35621-01:
(7*3)+(6*5)+(5*6)+(4*2)+(3*1)+(2*0)+(1*1)=93
93 % 10 = 3
So 35621-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H12N2.2ClH/c6-5-1-3-7-4-2-5;;/h5,7H,1-4,6H2;2*1H
35621-01-3Relevant academic research and scientific papers
Solvent-freeN-Boc deprotection byex situgeneration of hydrogen chloride gas
De Borggraeve, Wim M.,Gilles, Philippe,Van Mileghem, Seger,Verschueren, Rik H.
supporting information, p. 5782 - 5787 (2021/07/12)
An efficient, scalable and sustainable method for the quantitative deprotection of thetert-butyl carbamate (N-Boc) protecting group is described, using down to near-stoichiometric amounts of hydrogen chloride gas in solvent-free conditions. We demonstrate theex situgeneration of hydrogen chloride gas from sodium chloride and sulfuric acid in a two-chamber reactor, introducing a straightforward method for controlled and stoichiometric release of HCl gas. The solvent-free conditions allow deprotection of a wide variety ofN-Boc derivatives to obtain the hydrochloride salts in quantitative yields. The procedure obviates the need for any work-up or purification steps providing an uncomplicated green alternative to standard methods. Due to the solvent-free, anhydrous conditions, this method shows high tolerance towards acid sensitive functional groups and furnishes expanded functional group orthogonality.
