35653-80-6

Upstream product

• 350-46-9 4-Fluoronitrobenzene 
• 106-49-0 p-toluidine 
• 371-40-4 4-fluoroaniline 
• 352-15-8 4-fluoro-nitrosobenzene 

Downstream Products

• 1440358-03-1 C₂₃H₂₉FN₂ 
• 1440358-17-7 C₂₃H₂₉FN₂ 
• 1239969-21-1 C₂₀H₂₅FN₂Si 
• 1239969-20-0 C₂₀H₂₅FN₂Si 

Relevant academic research and scientific papers

Aromatic amine oxidation process for preparing aromatic azobenzene method

The invention relates to a method for preparing an aromatic azo compound by utilizing aromatic amine oxidation. In the method, air or oxygen serves as an oxygen source, and under the effect of a catalyst, aromatic amine is oxidized into the aromatic azo compound. The method is high in oxidization efficiency and product yield; the air or the oxygen serves as the oxygen source, and the method is economical and environmentally friendly. The product and the catalyst can be separated easily, and the aftertreatment is simple. The catalyst is easy to reuse, and the method has very good application prospect.

Oxidative coupling of anilines to azobenzenes using heterogeneous manganese oxide catalysts

We herein report the transition metal oxide-catalyzed synthesis of azobenzenes through the oxidative coupling of anilines. An octahedral molecular sieve of manganese oxide, OMS-2, exhibited the best activity and selectivity. Nine examples of symmetric azobenzenes and twenty unsymmetric ones were synthesized with 62-99% conversion and 64-99% selectivity. In the aniline cross-coupling reactions, the difference of the Hammett constants of two substituted groups (Δσ) determines the selectivity to unsymmetric azobenzenes, which are the major products at Δσ 0.32. In-depth studies reveal that the surface defect sites of the mixed-valence manganese oxide play a key role in facilitating electron transfer and activating molecular oxygen. The single-electron transfer (SET) reaction mechanism is proposed based on electron paramagnetic resonance and X-ray powder diffraction characterization.

Aryliminodimagnesium Reagents. XIV. Reactions with Nitrobenzenes Having Electronegative ortho-Substituents. Effects of Reaction Conditions on Condensation, Replacement, and Substitution

In reactions of ArN(MgBr)2 with o-MeO- and o-halo-substituted nitrobenzenes, types and yields of products were different from those in its reactions with m- and p-substituted substrates.Condensation (leading to unsymmetrical azoxy- and azobenzenes), o-substituent replacement, and nuclear substitution took place.Relative yields of products were greatly affected by substituents and reaction conditions. o-MeO and o-F favor replacement, while o-Cl, o-Br, and o-I favor substitution.Replacement and/or substitution predominate when small molar excess of reagent and low concentration are used, while condensation predominates when large molar excess of reagent and high concentration are used, which phenomenon is mechanistically discussed.

STUDIES ON THE MECHANISM OF THE OXIDATION OF AROMATIC PRIMARY AMINES WITH LEAD TETRAACETATE

The oxidation of eight substituted anilines with lead tetraacetate gives azo derivatives and products deriving from nucleophilic nuclear attack.A ligand transfer mechanism and a reaction path via aminium radical is suggested for these oxidations.