356566-58-0 Usage
Uses
Used in Pharmaceutical Industry:
4-(3,4-Difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid is used as a pharmaceutical intermediate for the development of new drugs. Its unique molecular structure and potential biological activity make it a valuable compound for further research and synthesis of therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 4-(3,4-Difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid serves as a key building block for the design and synthesis of novel compounds with potential therapeutic properties. Its structural features allow for the exploration of various chemical modifications to enhance its biological activity and selectivity.
Used in Drug Discovery:
4-(3,4-Difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid is utilized in drug discovery processes to identify new lead compounds with potential therapeutic effects. Its unique chemical structure provides a foundation for optimizing pharmacokinetic and pharmacodynamic properties, leading to the development of innovative treatments for various diseases.
Used in Biochemical Studies:
In biochemical research, 4-(3,4-Difluorophenyl)-1,2,3,4-tetrahydro-6-methyl-2-oxo-5-pyrimidinecarboxylic acid is employed as a tool compound to study the interactions between small molecules and biological targets. Its potential biological activity allows researchers to investigate its binding affinity, selectivity, and mechanism of action, contributing to a better understanding of molecular recognition and signaling pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 356566-58-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,6,5,6 and 6 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 356566-58:
(8*3)+(7*5)+(6*6)+(5*5)+(4*6)+(3*6)+(2*5)+(1*8)=180
180 % 10 = 0
So 356566-58-0 is a valid CAS Registry Number.
356566-58-0Relevant academic research and scientific papers
Solid-Phase Synthesis of Dihydropyrimidones via N-Acyliminium Ion-Based α-Ureidoalkylations
Valverde, Maria Garcia,Dallinger, Doris,Kappe, C. Oliver
, p. 741 - 744 (2007/10/03)
The synthesis of 4-aryl-2-(thioxo)oxo-3,4-dihydropyrimidine-5-carboxylic acids is reported using two orthogonal solid-phase variations of the Biginelli condensation. In the first method, polymer-bound β-ketoesters are treated with aromatic aldehydes and urea under acidic conditions. The transient N-acyliminium ion that is initially formed from the aldehyde and urea precursors, is then intercepted by the resin-bound β-ketoesters. In an alternative approach, resin-bound β-ketoesters are condensed with aldehydes and O-methylisourea under basic conditions. Both orthogonal condensation procedures provide fair to excellent overall yields of the desired target structures.
