35666-79-6

Basic information

• Product Name: 2-methyl-2-pyrrolidin-1-ylpropanenitrile
• Synonyms: 2-methyl-2-pyrrolidin-1-ylpropanenitrile;1-Pyrrolidineacetonitrile, α,α-dimethyl-
• CAS NO: 35666-79-6
• Molecular Formula: C₈H₁₄N₂
• Molecular Weight: 138.21016
• Mol File: 35666-79-6.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 67-70 °C(Press: 0.5 Torr)
• Appearance: /
• Density: 0.991±0.06 g/cm3(Predicted)
• PKA: 6.73±0.20(Predicted)
• CAS DataBase Reference: 2-methyl-2-pyrrolidin-1-ylpropanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-2-pyrrolidin-1-ylpropanenitrile(35666-79-6)
• EPA Substance Registry System: 2-methyl-2-pyrrolidin-1-ylpropanenitrile(35666-79-6)

Safety Data

• Hazardous Substances Data: 35666-79-6(Hazardous Substances Data)

Upstream product

• 123-75-1 pyrrolidine 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 
• 7677-24-9 trimethylsilyl cyanide 
• 67-64-1 acetone 
• 151-50-8 potassium cyanide 

Downstream Products

• 896119-95-2 (+/-)-[2-methyl-1-phenyl-2-(1-pyrrolidinyl)propyl]amine 
• 97061-77-3 C₁₄H₂₀N₂ 

Relevant articles and documents

Heterogeneously catalysed Strecker-type reactions using supported Co(ii) catalysts: Microwave vs. conventional heating

A range of α-aminonitriles could be efficiently prepared from various aldehydes/ketones and primary or secondary amines using a highly active and stable Co(ii) complex supported on different mesoporous supports at both room temperature and low temperature microwave irradiation under solventless conditions. Catalysts were also highly reusable under the investigated reaction conditions and could be reused at least 10 times without loss of catalytic activity. The Royal Society of Chemistry.

PYRROLIDINE DERIVATIVES HAVING ACTIVITY AT THE GLYT1 TRANSPORTER

The succinate and napadisylate salts and solvates of 2-(Methyloxy)-/V-[2-methyl-1-phenyl-2- (1-pyrrolidinyl)propyl]-4,6-bis(trifluoromethyl)benzamide,6-bis(trifluoromethyl)benzamide napadisylate, and uses thereof in the treatment of disorders relating to

GLYCINE TRANSPORTER INHIBITING COMPOUNDS AND USES IN MEDICINE

Compounds of formula (I) and salts and solvates thereof are provided: wherein either 1 ) R1, R2, R3 and R4 and all methyl, or 2) R1 and R2 form a pyrrolidinyl group and R3 and R4 are both methyl, or 3) R1 and R2 are both methyl and R3 and R4 together form