35756-26-4Relevant academic research and scientific papers
A one-pot synthesis of 1,4-dithiins and 1,4-benzodithiins from ketones using the recyclable reagent 1,1′-(ethane-1,2-diyl)dipyridinium bistribromide (EDPBT)
Murru, Siva,Kavala, Veerababurao,Singh,Patel, Bhisma K.
, p. 1007 - 1011 (2008/02/04)
A novel access to 1,4-dithiins and 1,4-benzodithiins from the corresponding ketones in one-pot using the recyclable reagent, 1,1′-(ethane-1,2-diyl)dipyridinium bistribromide (EDPBT) is described. This method is mild, simple, environmentally benign and is
Rapid method for the ring expansion of 1,3-dithiolanes and 1,3-dithianes with tert-rutyl hypochlorite
Arote, Nitin D.,Telvekar, Vikas N.,Akamanchi
, p. 2935 - 2938 (2007/10/03)
A new method for the ring expansion of 1,3-dithiolanes and 1,3-dithianes to dihydro-1,4-dithiins and dihydro-1,4-dithiepines, respectively, using lert-butyl hypochlorite at room temperature is described. The salient features of the protocol include mild r
A first example using o-iodoxybenzoic acid (IBX) in combination with tetraethylammonium bromide (TEAB) for ring expansion of 1,3-dithiolanes and 1,3-dithianes
Shukla, Vidyanand G.,Salgaonkar, Paresh D.,Akamanchi, Krishnacharya G.
, p. 1483 - 1485 (2007/10/03)
A novel one-pot procedure for the synthesis of dihydro-1,4-dithiins and dihydro-1,4-dithiepines from the corresponding 1,3-dithiolanes and 1,3-dithianes using o-iodoxybenzoic acid (IBX) in combination with tetraethylammonium bromide (TEAB) is described. T
2,3-Dihydro-dithiin and -dithiepine-1,1,4,4-tetroxides: Small molecule non-peptide antagonists of the human galanin hGAL-1 receptor
Scott, Malcolm K.,Ross, Tina M.,Lee, Daniel H. S.,Wang, Hoau-Yan,Shank, Richard P.,Wild, Kenneth D.,Davis, Coralie B.,Crooke, Jeffrey J.,Potocki, Alexander C.,Reitz, Allen B.
, p. 1383 - 1391 (2007/10/03)
The neuropeptide galanin modulates several physiological functions such as cognition, learning, feeding behavior, and depression, probably via the galanin 1 receptor (GAL-R1). Using an HTS assay based on 125I-human galanin binding to the human
Reactivity of ethanediyl S,S-acetals; 2. Synthesis of 2,3-dihydro-1,4-dithiins
Caputo,Ferreri,Palumbo
, p. 223 - 224 (2007/10/02)
A new, reliable one-step synthesis of 2,3-dihydro-1,4-dithiins from ethanediyl S,S-acetal derivatives of carbonyl compounds is reported.
gem-Difluorination vs 1,3-Dithiolane-Dihydro-1,4-dithiin Rearrangement. The Role of Benzylic Carbons
Jekoe, Jozsef,Timar, Tibor,Jaszberenyi, Joseph Cs.
, p. 6748 - 6751 (2007/10/02)
1,3-Dithiolanes bearing a phenyl or substituted aromatic group and a methyl (or methylene) group attached to C-2 cannot be gem-difluorinated with 1,3-dibromo-5,5-dimethylhydantoin (DBH) (or NBS) + HF/pyridine because a rapid 1,3-dithiolane-dihydro-1,4-dit
Ring Expansion Reaction of 1,3-Dithiolanes and 1,3-Oxathiolanes Using Tellurium Tetrachloride
Tani, Hiroyuki,Inamasu, Tokuo,Tamura, Rui,Suzuki, Hitomi
, p. 1323 - 1326 (2007/10/02)
On treatment with tellurium tetrachloride in dichloromethane at room temperature, 1,3-dithiolanes and 1,3-oxathiolanes undergo smooth ring expansion to give dihydro-1,4-dithiin and dihydro-1,4-oxathiin derivatives respectively in good to moderate yields.
Studies on the Formation of Dihydro-1,4-oxathiines by Halogenation of 1,3-Oxathiolanes.
Nevalainen, Vesa,Pohjala, Esko
, p. 1401 - 1421 (2007/10/02)
Formation of 5,6-dihydro-1,4-oxathiines (1a-g) by halogenation of 1,3-oxathiolanes (4a-g) was investigated.Moderate yields of (1) were obtained in systems in which the newly formed double bond of the heterocyclic ring was stabilised by conjugation.In addition to the dihydro-1,4-oxathiines (1a-g), their halogenated derivatives and some fused and spiro 1,4-oxathianes were produced as by-products.By-products of reactions were analysed by gas chromatography and mass-spectrometry.
THE REACTION OF ETHANEDIYL S,S-ACETALS WITH HALOGENES
Caputo, Romualdo,Ferreri, Carla,Palumbo, Giovanni,Capozzi, Giuseppe
, p. 2369 - 2376 (2007/10/02)
Cyclic thioacetals and thioketals (1,3-dithiolanes) are reported to react smoothly with halogens in a 1:1 molar ratio, at room temperature in anhydrous carbon tetrachloride.The mechanistic aspects of the reaction are considered and evidence is shown of the itermediacy of monocationic rather than the previously postulated dicatonic species in the cleavage reactions of 1,3-dithiolanes of aromatic ketones.
NON-STEREOSPECIFIC RING EXPANSIONS OF 5-MEMBERED HETEROCYCLIC SULFOXIDES
Ueda, Norihiro,Shimizu, Hiroshi,Kataoka, Tadashi,Hori, Mikio
, p. 757 - 760 (2007/10/02)
Non-stereospecific ring expansion reactions of 5-membered heterocyclic sulfoxides, 1,3-benzoxathiole sulfoxides, 1,3-benzodithiole sulfoxides, and 1,3-dithiolane sulfoxides having a heteroatom at β-position to the sulfinyl group with acetic anhydride or p-toluenesulfonic acid are described together with their reaction mechanism involving a sulfonium ion intermediate.
