357623-46-2

Basic information

• Product Name: 4,4'-[(4-cyanophenyl)methylene]-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol)
• Synonyms: 4,4'-[(4-cyanophenyl)methylene]-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol)
• CAS NO: 357623-46-2
• Molecular Weight: 461.523
• Mol File: 357623-46-2.mol

Chemical Properties

• CAS DataBase Reference: 4,4'-[(4-cyanophenyl)methylene]-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol)(CAS DataBase Reference)
• NIST Chemistry Reference: 4,4'-[(4-cyanophenyl)methylene]-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol)(357623-46-2)
• EPA Substance Registry System: 4,4'-[(4-cyanophenyl)methylene]-bis-(3-methyl-1-phenyl-1H-pyrazol-5-ol)(357623-46-2)

Safety Data

• Hazardous Substances Data: 357623-46-2(Hazardous Substances Data)

Upstream product

• 27420-41-3 2-hydroxy-4H-pyrido<1,2-a>pyrimidin-4-one 
• 105-07-7 4-cyanobenzaldehyde 
• 89-25-8 edaravone 
• 141-97-9 ethyl acetoacetate 
• 100-63-0 phenylhydrazine 

Relevant articles and documents

Poly(4-vinylpyridine)-supported dual acidic ionic liquid: An environmentally friendly heterogeneous catalyst for the one-pot synthesis of 4,4'-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols)

A poly(4-vinylpyridine)-supported Bronsted ionic liquid was easily prepared from its starting materials and used as a novel, highly efficient, and reusable heterogeneous catalytic system for the synthesis of 4,4'-(arylmethylene)bis(3- methyl-1-phenyl-1H-p

Polyethylene glycol-bonded triethylammonium l-prolinate: A new biodegradable amino-acid-based ionic liquid for the one-pot synthesis of bis(pyrazolyl)methanes as DNA binding agents

Polyethylene glycol-bonded triethylammonium l-prolinate ([PEG-TEA]LP) was prepared as a new, highly efficient, reusable and biodegradable amino-acid-based ionic liquid catalyst using cheap and easily accessible starting materials. The [PEG-TEA]LP chemical

Synthesis and Application of Graphene Oxide-supported Aluminium Chloride as a Novel and an Environmentally Friendly Catalyst for the Preparation of Bis(pyrazolyl)methanes

The immobilization of AlCl3, an extremely hygroscopic Lewis acid, on graphene oxide as a support material with a high surface area was studied. The obtained solid material was characterized by FTIR spectroscopy, TGA/DTA analysis, field emission

Non-covalent supported of L-proline on Graphene Oxide/Fe3O4 Nanocomposite: A novel, highly efficient and superparamagnetically separable catalyst for the synthesis of bis-pyrazole derivatives

A superparamagnetic graphene oxide/Fe3O4/L-proline nano hybrid that was obtained from the non-covalent immobilization of L-proline on graphene oxide/Fe3O4 nanocomposite was used as a new magnetically separable c

An efficient one-pot synthesis of highly functionalized benzylpyrazolyl pyrido[1,2-a]pyrimidine derivatives using CuFe2O4 nanoparticles under solvent-free conditions

Abstract: An efficient and green protocol for the synthesis of novel benzylpyrazolyl pyrido[1,2-a]pyrimidine derivatives via three-component reaction of aryl aldehydes, 2-hydroxy-4H-pyrido[1,2-a]pyrimidine-4-ones, and 3-methyl-1-phenyl-1H-pyrazol-5-one has been reported using a magnetically separable and reusable heterogeneous copper ferrite (CuFe2O4) nano-catalyst under solvent-free conditions. CuFe2O4 nanoparticles were characterized by FT-IR, powder X-ray diffraction and transmission electron microscopy. Graphical Abstract: An efficient one-pot synthesis of highly functionalized benzylpyrazolyl pyrido[1,2-a]pyrimidine derivatives using CuFe2O4 nanoparticles under solvent-free conditions.

Mn-[4-Chlorophenyl-Salicylaldimine-Methylpyranopyrazole]Cl2 as a Novel Nanostructured Schiff Base Complex and Catalyst

Mn-[4-chlorophenyl-salicylaldimine-methylpyranopyrazole]Cl2 ([Mn-4CSMP]Cl2) as nano-Schiff base complex was prepared and fully characterized by Fourier transform infrared spectroscopy, X-ray diffraction, thermal gravimetric analysis,

One-pot efficient pseudo-five-components synthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) at room temperature assisted by K2CO3

A convenient approach for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) by an efficient one-pot reaction of aromatic aldehydes, phenylhydrazine, and ethyl acetoacetate by using substoichiometric amount of K2COsu

Cyclocondensation-Knoevenagel–Michael Domino reaction of phenyl hydrazine, acetoacetate derivatives and aryl aldehydes over acetic acid functionalized ionic liquid

Abstract: An efficient solvent-free protocol for the synthesis of 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s via one-pot pseudo five-component condensation reaction of phenyl hydrazine, ethylacetoacetate, and aryl aldehydes in the presence of acetic acid functionalized pyridinium salt (1-(carboxymethyl)pyridinium chloride {[cmpy]Cl}) as reusable catalyst has been reported. Moreover,1 H and13C NMR, mass, CHN analysis, Fourier transform infrared spectroscopy, scanning electron microscope, X-ray diffraction analysis, and calculation of interplaner distance of the catalysts have been studied in this work. Graphical Abstract: [Figure not available: see fulltext.]

Design and Characterization of l-Prolinate-Amberlite as a Novel Heterogeneous Organocatalyst and Its Catalytic Application in the Synthesis of Pyrazol-Derivates

The [Amb]l-prolinate obtained from the immobilization of l-prolinate anion onto amberlite IRA900OH, was used as a new organocatalyst for the efficient synthesis of 4,4′-(arylmethylene)-bis-(1H-pyrazol-5-ol) derivatives. The prepared heterogeneous organoca

Cu-isatin schiff base complex supported on magnetic nanoparticles as an efficient and recyclable catalyst for the synthesis of bis(indolyl)methanes and bis(pyrazolyl)methanes in aqueous media

Cu-isatin Schiff base supported on γ-Fe2O3as a new catalyst was synthesized and characterized by different methods such as SEM, TEM, XRD, TGA, FT-IR, ICP, VSM and CHN analysis. It was used as a reusable heterogeneous catalyst for the