35857-66-0

Usage

Uses

Used in Chemical Synthesis:
3-CHLORO-1-(3,4-DICHLOROPHENYL)-1-PROPANONE is used as a reagent and intermediate in chemical synthesis for its ability to participate in a range of reactions, contributing to the formation of complex organic compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 3-CHLORO-1-(3,4-DICHLOROPHENYL)-1-PROPANONE is utilized as a key intermediate in the synthesis of various drugs, playing a crucial role in the development of new medicinal compounds.
Used in Agrochemical Production:
3-CHLORO-1-(3,4-DICHLOROPHENYL)-1-PROPANONE is employed in the production of agrochemicals, where it serves as a vital component in the creation of pesticides and other agricultural chemicals to protect crops and enhance yields.
Used in Research and Development:
In the realm of research and development, particularly within the fields of organic chemistry and chemical synthesis, 3-CHLORO-1-(3,4-DICHLOROPHENYL)-1-PROPANONE is used for its potential to advance scientific understanding and facilitate the discovery of new chemical processes and products.

InChI:InChI=1/C9H7Cl3O/c10-4-3-9(13)6-1-2-7(11)8(12)5-6/h1-2,5H,3-4H2

Upstream product

• 95-50-1 1,2-dichloro-benzene 
• 625-36-5 2-chloropropionyl chloride 

Downstream Products

• 62847-55-6 1-(3,4-dichloro-phenyl)-3-nitro-propan-1-one 
• 107049-58-1 1-Chloro-3-(3,4-dichloro-phenyl)-pentan-3-ol 
• 113696-78-9 4-Chloro-2-(3,4-dichloro-phenyl)-butan-2-ol 
• 113696-80-3 1-Chloro-3-(3,4-dichloro-phenyl)-heptan-3-ol 
• 113696-83-6 4-Chloro-2-(3,4-dichloro-phenyl)-1-phenyl-butan-2-ol 
• 113696-79-0 1-Chloro-3-(3,4-dichloro-phenyl)-hexan-3-ol 
• 113696-81-4 1-Chloro-3-(3,4-dichloro-phenyl)-octan-3-ol 
• 113696-82-5 1-Chloro-3-(3,4-dichloro-phenyl)-nonan-3-ol 
• 113720-98-2 1-(3,4-dichlorobenzoylethyl)-4-(3,4,5-trimethoxybenzyl)piperazine dihydrochloride 
• 113696-63-2 2-(3,4-Dichloro-phenyl)-4-[4-(2,3,4-trimethoxy-benzyl)-piperazin-1-yl]-butan-2-ol; hydrochloride 
• 1346461-00-4 C₁₃H₁₉Cl₂NO*ClH 
• 1346460-37-4 3-(3,4-dichlorophenyl)-N,N-diethyl-3-(pyrrolidin-1-yl)propan-1-amine hydrochloride 
• 75144-12-6 1-(3,4-dichlorophenyl)-3-dimethylamino-1-propanone hydrochloride 

Relevant academic research and scientific papers

Synthesis and antidepressant activity of a series of arylalkanol and aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7

A series of arylalkanol and aralkyl piperazine derivatives have been synthesized and evaluated for 5-HT reuptake inhibitory abilities and binding affinities at the 5-HT1A/5-HT7 receptors. Antidepressant activities of the compounds in

Synthesis and pharmacological investigation of aralkyl diamine derivatives as potential triple reuptake inhibitors

A series of aralkyl diamine derivatives were designed, synthesized, and evaluated for their triple reuptake inhibitory abilities. Compounds 18c (5-HT, NE, DA, IC50 = 389, 69, 238 nM), 36a (5-HT, NE, DA, IC50 = 378, 477, 247 nM), and

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANTS

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

ARALKYL DIAMINE DERIVATIVES AND USES THEREOF AS ANTIDEPRESSANT

Aralkyl diamine derivative of the following formula, pharmaceutically acceptable salts or uses thereof as antidepressants. The derivatives have triplex inhibiting activities of the reuptake of 5-HT, dopamine and noradrenalin, which can be administered to the patients in need of such treatment in the form of compositions orally or injectedly et al.

Synthesis and antidepressant activity of arylalkanol-piperidine derivatives as triple reuptake inhibitors

A series of arylalkanol-piperidine derivatives was synthesized, and their triple reuptake inhibition and in vivo activities have been evaluated. Among them, compounds 2a, 2j, 2k, 2m and 2n exhibited high potency for 5-HT, NA and DA transporters. Optimized compounds 2j and 2m showed significant reduction of immobility time compared to that of vehicle in the mouse tail suspension test (TST) test at doses ranging from 10 to 50 mg/kg po, and were not generally motor stimulants at 50 mg/kg dose. In addition, compounds 2j and 2m displayed desirable pharmacokinetic properties in SD rats.