3587-57-3Relevant academic research and scientific papers
3-Alkoxymethyl-1-(1R,2S,5R)-(-)-menthoxymethylimidazolium salts-based chiral ionic liquids
Feder-Kubis, Joanna,Kubicki, MacIej,Pernak, Juliusz
experimental part, p. 2709 - 2718 (2011/02/16)
A new group of imidazolium salt-based chiral ionic liquids have been prepared and characterized. The chiral ionic liquids obtained are stable in air, in contact with water and popular organic solvents. Their physicochemical properties, single-crystal X-ray structures, antimicrobial activities, and antielectrostatic effects have been determined. The chiral ionic liquids synthesized have proven to represent not only potential new solvents in asymmetric synthesis but also effective disinfectants with antielectrostatic activity.
Ionic liquids with symmetrical dialkoxymethyl-substituted imidazolium cations
Pernak, Juliusz,Sobaszkiewicz, Kinga,Foksowicz-Flaczyk, Joana
, p. 3479 - 3485 (2007/10/03)
A new one-step procedure is described for the synthesis of disubstituted imidazolium chlorides. 1,3-Dialkoxymethylimidazolium chlorides thus obtained can be employed as synthetic precursors of symmetrical ILs. The salts have been found to exhibit antimicrobial activity and an antielectrostatic effect. Their densities and viscosities have been determined and are reported herein. It has also been demonstrated that the ILs can be decomposed using an aqueous solution of KMnO4. For each IL, the permanganate index (IMn) has been estimated, which varies with the structure of cation. The only limitation of IMn is the degree to which the IL dissolves in water.
The Antielectrostatic Effect of N-Alkanol-N-alkoxymethyl-N,N- dimethylammonium Chlorides and Their Ester Derivatives
Pernak,Chwala,Syguda,Pozniak
, p. 1263 - 1274 (2007/10/03)
Several new quaternary ammonium chlorides, analogues of choline, were prepared by reaction of 2-(dimethylamino)ethanol and its derivatives with chloromethyl alkyl ethers. The obtained chlorides were examined in respect to their antielectrostatic effects:
Synthesis and anti-microbial activities of choline-like quaternary ammonium chlorides
Pernak, Juliusz,Chwala, Przemyslaw
, p. 1035 - 1042 (2007/10/03)
New choline-like quaternary ammonium chlorides were obtained. The work-up procedure of synthesis was quick and efficient. The obtained chlorides showed anti-microbial activities. Quaternary ammonium chlorides derivatives of deanol esters exhibited strong
Synthesis and anti-microbial activities of some pyridinium salts with alkoxymethyl hydrophobic group
Pernak, Juliusz,Kalewska, Joanna,Ksycinska, Hanna,Cybulski, Jacek
, p. 899 - 907 (2007/10/03)
A novel class of functionalised cationic surfactant has been obtained. The work-up procedure of synthesis is very simple, the yield is high and the pyridinium salts with alkoxymethyl hydrophobic group are easily purified. All the salts examined showed anti-microbial activities. Some of them exhibited strong activity and wide anti-bacterial spectra similar to the activity of benzalkonium chloride. The relationship between chemical structure and anti-microbial activity was analysed by the QSAR method.
2,5,6,7-tetranor-4,8-inter-m-phenylene PGI2 derivatives
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, (2008/06/13)
Disclosed herein are novel prostaglandin I2 (PGI2) derivatives exhibiting excellent in vivo duration and activities, said derivatives being represented by the general formula: STR1 wherein R1, X, R2 and R3 are as defined herein.
Hydantoin derivatives as potential antiinflammatory agents
Schulte,Von Weissenborn,Kwon
, p. 25 - 31 (2007/10/05)
The hydantoins 2a-c and three hydantoic acids were synthesized and their anti-inflammatory properties were determined in the rat paw oedema test. Neither 1-phenyl-sulphonyl-5,5-diphenylhydantoin, which has been described as an inflammatory, nor any of the other compounds, showed significant anti-inflammatory activity.
