505-84-0Relevant academic research and scientific papers
Novel synthesis method of alkoxymethylamine compound
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Paragraph 0055; 0056, (2019/10/01)
The invention relates to a novel synthesis method of an alkoxymethylamine compound. The novel synthesis method comprises the steps: (1) dehydrating formaldehyde HCHO and alcohol R1OH by carrying out an aldolization under the action of an acid catalyst to obtain dialkoxymethane; and (2) carrying out a hydrocarbylation reaction on dialkoxymethane obtained in step (1) and substituted amine R2-NH2 toremove alcohol to obtain an alkoxymethyl substituent amine compound N-R1 oxymethyl-N-R2 amine. The synthesis method disclosed by the invention is simple in operation and high in yield reaching 92% orabove; and compared with the prior art, the novel synthesis method has the advantages that no acid wastewater, waste salts and chloromethyl alkyl ether serving as a cancerogen are greatly generated, the environment protection cost is favorably reduced, and the industrial prospect is higher.
Three Binary Azeotropic Systems for 1-(Methoxymethoxy)-propane, 1-(Ethoxymethoxy)-propane, and Methoxy(methoxymethoxy)methane with Three Alcohols at 101.33 kPa: Experimental Data, Correlation, and Purification
Song, Yu-He,Hou, Xing-Ming,Song, Juan,Zhang, Yue,Wang, Jie,Wei, Ping-He,Li, Cun-Fu
, p. 138 - 146 (2018/01/18)
The isobaric vapor-liquid equilibrium (VLE) data for three binary systems of 1-(methoxymethoxy)-propane and ethanol, 1-(ethoxymethoxy)-propane and 1-butanol, methoxy(methoxymethoxy)methane and 1-propanol at 101.33 kPa were measured using an improved Rose still. Three minimum boiling azeotropes were found for three binary systems containing ethanol, 1-butanol, and 1-propanol for which the azeotropic temperature and composition are 349.35 K and 70.95 mol % (ethanol), 384.02 K and 36.02 mol % (1-butanol), 368.68 K and 69.26 mol % (1-propanol), at 101.33 kPa, respectively. The VLE measurements were correlated by the Van Laar, Wilson, and nonrandom two-liquid models, and the results showed that the measurements had a good correlation by using thethree models for the three binary systems, respectively. The measurements of these three binary systems were thermodynamic as checked by the Herington semiempirical method.
Br?nsted-acidic ionic liquids as efficient catalysts for the synthesis of polyoxymethylene dialkyl ethers
Song, Heyuan,Kang, Meirong,Jin, Fuxiang,Wang, Guoqin,Li, Zhen,Chen, Jing
, p. 853 - 861 (2017/05/24)
Acetalation of formaldehyde (HCHO) with dialkyl formal or aliphatic alcohol to prepare polyoxymethylene dialkyl ethers (RO(CH2O)nR, n ≥ 1) catalyzed by Br?nsted-acidic ionic liquids has been developed. The correlation between the structure and acidity activity of various ionic liquids was studied. Among the ionic liquids investigated, 1-(4-sulfonic acid)butyl-3-methylimidazolium hydrogen sulfate ([MIMBs]HSO4) exhibited the best catalytic performance in the reaction of diethoxymethane (DEM1) with trioxane. The influences of ionic liquid loading, molar ratio of DEM1 to HCHO, reaction temperature, pressure, time, and reactant source on the catalytic reaction were explored using [MIMBs]HSO4 as the catalyst. Under the optimal conditions of n([MIMBs]HSO4):n(DEM1):n(HCHO) = 1:80:80, 140 °C, and 4 h, the conversion of HCHO and selectivity for DEM2–8 were 92.6% and 95.1%, respectively. The [MIMBs]HSO4 catalyst could be easily separated and reused. A feasible mechanism for the catalytic performance of [MIMBs]HSO4 was proposed.
An efficient and convenient method for the synthesis of dialkoxymethanes using kaolinite as a catalyst
Pathak, Devendra D.,Gerald, J. Joe
, p. 1557 - 1561 (2007/10/03)
A one pot synthesis of dialkoxymethanes (2a-h) is described from the reaction of alcohols (1a-h) with paraformaldehyde under reflux in the presence of catalytic amount of kaolinite.
