358741-44-3Relevant academic research and scientific papers
Study of the transient reactive Pd(IV) intermediate in the Pd(OAc) 2-catalyzed oxidative coupling reaction system by electrospray ionization tandem mass spectrometry
Zhu, Wei,Wang, Haoyang,Peng, Haihui,Liu, Guosheng,Guo, Yinlong
, p. 371 - 376 (2013)
Pd-catalyzed oxidative coupling reaction was of great importance in the aromatic C - H activation and the formation of new C - O and C - C bonds. Sanford has pioneered practical, directed C - H activation reactions employing Pd(OAc)2 as catalys
Copper-catalyzed aromatic C-H alkoxylation with alcohols under aerobic conditions
Lu, Wenkui,Xu, Hui,Shen, Zengming
, p. 1261 - 1267 (2017)
An efficient protocol for copper-catalyzed aromatic C-H alkoxylation with alcohols has been developed under aerobic conditions. The protocol provides a complementary method to couple arenes and alcohols to furnish aromatic ethers. The advantages of this method are the employment of a cheap Cu(OAc)2 catalyst, oxygen as the terminal oxidant and alcohol as both an alkoxy reagent and a solvent. Notably, the catalytic amount of benzoic acid plays a significant role in this transformation.
Chromium-Catalyzed Reductive Cleavage of Unactivated Aromatic and Benzylic C-O Bonds
Yuan, Shuqing,Ling, Liang,Tang, Jinghua,Luo, Meiming,Zeng, Xiaoming
supporting information, p. 3343 - 3350 (2021/07/02)
Reductive cleavage of aromatic and benzylic C-O bonds by chromium catalysis is reported. This deoxygenative reaction was promoted by low-cost CrCl 2precatalyst combined with poly(methyl hydrogen siloxane) as the mild reducing agent, providing a strategy in forming reduced motifs by cleavage of unactivated C-O bonds. A range of functional groups such as bromide, chloride, fluoride, hydroxyl, amino, and alkoxycarbonyl can be retained in the reduction.
Directing Group-Promoted Inert C?O Bond Activation Using Versatile Boronic Acid as a Coupling Agent
Ambre, Ram,Wang, Ting-Hsuan,Xian, Anmei,Chen, Yu-Shiuan,Liang, Yu-Fu,Jurca, Titel,Zhao, Lili,Ong, Tiow-Gan
supporting information, p. 17021 - 17026 (2020/11/30)
A simple Ni(cod)2 and carbene mediated strategy facilitates the efficient catalytic cross-coupling of methoxyarenes with a variety of organoboron reagents. Directing groups facilitate the activation of inert C?O bonds in under-utilized aryl methyl ethers enabling their adaptation for C?C cross-coupling reactions as less toxic surrogates to the ubiquitous haloarenes. The method reported enables C?C cross-coupling with readily available and economical arylboronic acid reagents, which is unprecedented, and compares well with other organoboron reagents with similarly high reactivity. Extension to directing group assisted chemo-selective C?O bond cleavage, and further application towards the synthesis of novel bifunctionalized biaryls is reported. Key to the success of this protocol is the use of directing groups proximal to the reaction center to facilitate the activation of the inert C?OMe bond.
Au(III)-aryl intermediates in oxidant-free C-N and C-O cross-coupling catalysis
Serra, Jordi,Parella, Teodor,Ribas, Xavi
, p. 946 - 952 (2017/02/10)
Au(iii)-aryl species have been unequivocally identified as reactive intermediates in oxidant-free C-O and C-N cross coupling catalysis. The crystal structures of cyclometalated neutral and cationic Au(iii) species are described and their key role in 2 ele
Copper-catalyzed dehydrogenative coupling of arenes with alcohols
Bhadra, Sukalyan,Matheis, Christian,Katayev, Dmitry,Goo?en, Lukas J.
supporting information, p. 9279 - 9283 (2013/09/12)
What a couple! Arenes functionalized with donating groups undergo oxidative dehydrogenative coupling with alcohols in the presence of a copper/silver catalyst system. This intermolecular C-H alkoxylation provides a convenient synthetic route to the important class of aryl ethers. The catalyst system also allows the alkoxylation of benzylic C-H groups with formation of benzyl alkyl ethers. Copyright
Oxidative coupling of arylboronic acids with arenes via Rh-catalyzed direct C-H arylation
Vogler, Thomas,Studer, Armido
, p. 129 - 131 (2008/09/16)
Oxidative coupling of three different arenes and a thiophene derivative with various arylboronic acids was achieved with a [RhCl(C2H 4)2]2/P[p-(CF3)C6H 4]3 catalyst sy
