358751-02-7

Upstream product

• 67-56-1 methanol 
• 358751-00-5 3-(but-3-en-1-yl)benzaldehyde 
• 67073-72-7 3-bromobenzaldehyde dimethyl acetal 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 107658-28-6 methyl 3-(trifluoromethylsulfonyloxy)benzoate 

Downstream Products

• 111393-29-4 methyl 3-(3-oxopropyl)benzoate 
• 286933-10-6 3-but-3-enyl-benzoic acid 
• 358751-18-5 methyl 1-hydroxyindane-5-carboxylate 

Relevant academic research and scientific papers

Macrocyclic Compounds Useful as Bace Inhibitors

The invention relates to novel macrocyclic compounds of the formula (I), in which all of the variables are as defined in the specification, the number of ring atoms included in the macrocyclic ring being 14, 15, 16 or 17, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.

Synthesis of xanthenes, Indanes, and tetrahydronaphthalenes via intramolecular phenyl-carbonyl coupling reactions

Benzaldehydes and acetophenones bearing tethered carbonyl chains underwent the intramolecular phenyl-carbonyl coupling reactions, by mediation of samarium diiodide and hexamethylphosphoramide, to afford the xanthenes and fused benzocarbocyclic compounds c