35883-55-7Relevant academic research and scientific papers
Acetylenic Ester Promoted Tandem Ring Opening of Dienyl Thiazolidin-4-ones and Cyclizations: A Facile and Chemoselective Synthesis of Functionalized Pyridine-2-carboxylates
Kuila, Bilash,Kumar, Kapil,Mahajan, Dinesh,Singh, Prabhpreet,Bhargava, Gaurav
supporting information, p. 509 - 512 (2017/12/06)
Acetylenic ester promoted ring opening of dienyl-thiazolidin-4-ones and subsequent electrocyclization affords 5-phenyl-6-aryl pyridine-2-carboxylates in good to excellent yields.
HETEROAROMATIC COMPOUNDS HAVING SPHINGOSINE-1-PHOSPHATE (S1P) RECEPTOR AGONIST BIOLOGICAL ACTIVITY
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Page/Page column 19, (2008/06/13)
A novel compound having agonist activity at the S1P3 receptor which is represented by the formula I wherein X is selected from the group consisting of CR3, N and NO;Y is selected from the group consisting of CR3, N and NO;Z is selected from the group consisting of CR3, N and NO; and at least one of X, Y and Z is N or NO; V is O or NOR4 R1 is an aryl group;R2 is an aryl group;R3 is selected from the group consisting of H and alkyl; and 2 of said R3 groups may together form a cyclic alkyl ring having from 3 to 6 carbon atoms; R4 is selected from the group consisting of H and alkyl;a is 0 or an integer of from 1 to 6;b is 0 or 1;c is 0 or 1;f is 0 or an integer of 1 or 2;x is 0 or 1;y is 0 or an integer of from 1 to 3; andz is 0 or an integer of from 1 to 3.
Total synthesis of the thiopeptide antibiotic amythiamicin D
Hughes, Rachael A.,Thompson, Stewart P.,Alcaraz, Lilian,Moody, Christopher J.
, p. 15644 - 15651 (2007/10/03)
The thiopeptide (or thiostrepton) antibiotics are a class of sulfur containing highly modified cyclic peptides with interesting biological properties, including reported activity against MRSA and malaria. Described herein is the total synthesis of the thi
MONO- AND DI-SUBSTITUTED 3-AZA-α-TROPOLONES
Horiguchi, Yoshie,Sano, Takehiro,Tsuda, Yoshisuke
, p. 1509 - 1512 (2007/10/02)
New mono- and di-substituted 3-aza-α-tropolones 6 were synthesized by deethoxycarbonylation and subsequent DDQ oxidation of dihydroazatropolones 4.In methanol, 6 undergoes a skeletal rearrangement to give methyl pyridine-2-carboxylates 7, suggesting that
