35970-82-2

Basic information

• Product Name: 5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
• Synonyms: 5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione;5,6-Dimethyl-1H-thieno[2,3-d]pyrimidine-2,4-dione
• CAS NO: 35970-82-2
• Molecular Formula: C8H8N2O2S
• Molecular Weight: 196.23
• Mol File: 35970-82-2.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(35970-82-2)
• EPA Substance Registry System: 5,6-dimethylthieno[2,3-d]pyrimidine-2,4(1H,3H)-dione(35970-82-2)

Safety Data

• Hazardous Substances Data: 35970-82-2(Hazardous Substances Data)

Upstream product

• 4651-93-8 2-amino-4,5-dimethylthiophene-3-carboxylic acid methyl ester 
• 57-13-6 urea 
• 312607-42-4 ethyl 4,5-dimethyl-2-ureidothiophene-3-carboxylate 
• 4815-24-1 2-amino-4,5-dimethyl-3-thiophenecarboxylic acid ethyl ester 
• 4651-94-9 2-amino-4,5-dimethylthiophene-3-carbonitrile 
• 124-38-9 carbon dioxide 
• 51486-04-5 2-amino-4,5-dimethylthiophene-3-carboxamide 
• 109-90-0 ethyl isocyanate 
• 2909-38-8 m-chlorophenyl isocyanate 
• 614-68-6 2-tolyl isocyanate 
• 622-58-2 p-Tolylisocyanate 
• 103-71-9 phenyl isocyanate 
• 100-28-7 4-Nitrophenyl isocyanate 
• 42518-42-3 2,4-dichloro-5,6-dimethylthieno<2,3-d>pyrimidine 

Downstream Products

• 42518-42-3 2,4-dichloro-5,6-dimethylthieno<2,3-d>pyrimidine 

Relevant articles and documents

THIENO PYRIMIDINES AS FERROPORTIN INHIBITORS

The subject matter described herein is directed to ferroportin inhibitor compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds, and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis, and also kidney injuries.

Ionic liquid promoted synthesis of heterocycle-fused pyrimidine-2,4(1H,3H)-diones utilising CO2

An efficient ionic liquid system was developed for the preparation of various heterocycle-fused pyrimidine-2, 4(1H,3H)-diones in moderate to excellent yields (52–95%). It was found that [HDBN+][TFE?], a simple and easily prepared ionic liquid, could act as both the solvent and reaction promoter, and that the reactions could be efficiently carried out at atmospheric pressures of CO2.

Heteroarylpyrimindinedione derivative and use thereof

The invention provides a heteroarylpyrimindinedione derivative and use thereof. The heteroarylpyrimindinedione derivative comprises a compound with a structure shown as general formula I, and a pharmaceutically acceptable salt or hydrate thereof. The derivative is obtained by chemical synthesis, and pharmacological experiments prove that the active ligand with cannabinoid type II receptor CB2 can be used for preparation of drugs for prevention and mitigation of CB2 receptor-mediated diseases, and the drug is cannabinoid CB2 receptor agonist's agonist, partial agonist, inverse agonist or antagonist. And the general structural formula I is shown as the specification.