36062-86-9

Usage

Appearance

Yellow crystalline solid

Solubility

Insoluble in water, soluble in organic solvents

Potential use

Reagent in organic synthesis

Precursor

To other tellurium-containing compounds

Applications

Studied for anti-cancer and anti-microbial properties

Toxicity

Known to be toxic, should be handled with caution

Upstream product

• 106-39-8 bromochlorobenzene 
• 744142-42-5 4-Chloro-benzenetellurol 
• 637-87-6 1-Chloro-4-iodobenzene 
• 108-90-7 chlorobenzene 
• 1679-18-1 4-Chlorophenylboronic acid 

Downstream Products

• 101220-69-3 1-Chloro-4-difluoromethyltellanyl-benzene 
• 2050-68-2 4,4'-dichlorobiphenyl 
• 274925-85-8 C₆H₄ClITe 
• 1110718-25-6 (S)-dimethyl 2-(3-(4-chlorophenyltellanyl)propanamido)succinate 
• 1071469-60-7 C₂₂H₁₅ClSeTe 
• 1071469-46-9 C₂₂H₁₅ClTe₂ 
• 1167433-50-2 C₁₇H₁₇ClN₂O₆Te 
• 41923-50-6 bis(4‐chlorophenyl)tellane 
• 59130-72-2 (4-chlorophenyl)(phenylethynyl)tellane 
• 1616766-52-9 O,O-di-n-butyl Te-(4-chlorophenyl) phosphorotelluroate 

Relevant academic research and scientific papers

Synthesis, Mechanism Elucidation and Biological Insights of Tellurium(IV)-Containing Heterocycles

Inspired by the synthetic and biological potential of organotellurium substances, a series of five- and six-membered ring organotelluranes containing a Te?O bond were synthesized and characterized. Theoretical calculations elucidated the mechanism for the oxidation-cyclization processes involved in the formation of the heterocycles, consistent with chlorine transfer to hydroxy telluride, followed by a cyclization step with simultaneous formation of the new Te?O bond and deprotonation of the OH group. Moreover, theoretical calculations also indicated anti-diastereoisomers to be major products for two chirality center–containing compounds. Antileishmanial assays against Leishmania amazonensis promastigotes disclosed 1,2λ4-oxatellurane LQ50 (IC50=4.1±1.0; SI=12), 1,2λ4-oxatellurolane LQ04 (IC50=7.0±1.3; SI=7) and 1,2λ4-benzoxatellurole LQ56 (IC50=5.7±0.3; SI=6) as more powerful and more selective compounds than the reference, being up to four times more active. A stability study supported by 125Te NMR analyses showed that these heterocycles do not suffer structural modifications in aqueous-organic media or at temperatures up to 65 °C.

Modulating Chalcogen Bonding and Halogen Bonding Sigma-Hole Donor Atom Potency and Selectivity for Halide Anion Recognition

A series of acyclic anion receptors containing chalcogen bond (ChB) and halogen bond (XB) donors integrated into a neutral 3,5-bis-triazole pyridine scaffold are described, in which systematic variation of the electronic-withdrawing nature of the aryl sub

Synthetic method of diaryl ditellurium ether compound

The invention relates to a synthetic method of a diaryl ditellurium ether compound. The method comprises the following steps: putting phenylboronic acid or derivatives thereof, elemental tellurium, trimethylcyano silane and an organic solvent into a reaction container to obtain a mixed solution, heating the mixed solution to 110-140 DEG C, performing stirring to react for 18-30 hours at the temperature to obtain a reaction solution, and carrying out aftertreatment to obtain the diaryl ditellurium ether compound, the ratio of the phenylboronic acid or the derivative thereof to the elemental tellurium to the trimethylnitrile silane is (7-9): (8-10): 1. The synthetic method of the diaryl ditellurium ether compound has the following beneficial effects: 1, the reaction can be performed withoutmetal participation, so that the synthetic method is more environment-friendly and lower in cost; 2, the compatibility of a substrate is good; and 3, the preparation process is simple and easy to operate.

Pentafluoro(aryl)-λ6-tellanes and Tetrafluoro(aryl)(trifluoromethyl)-λ6-tellanes: From SF5 to the TeF5 and TeF4CF3 Groups

The TeF5 group is significantly underexplored as a highly fluorinated substituent on an organic framework, despite it being a larger congener of the acclaimed SF5 group. In fact, only one aryl-TeF5 compound (phenyl-TeFsub

Iron-catalyzed formation of C-Se and C-Te bonds through cross coupling of aryl halides with Se(0) and Te(0)/nano-Fe3O4@GO

The formation of C-Se and C-Te bonds is of synthetic and biological importance. Graphene oxide based nano-Fe3O4 (nano-Fe 3O4@GO) is used as a reusable catalyst for the efficient synthesis of diselenides and ditellurides, through cross coupling of Se(0) or Te(0) with aryl iodides. The magnetic heterogeneous catalyst could be easily recovered and reused many times without significant loss of catalytic activity. In addition the superiority of nano-Fe3O4@GO over pristine nano-Fe3O4 is established. Georg Thieme Verlag Stuttgart. New York.

Microwave-assisted one-pot synthesis of symmetrical diselenides, ditellurides and disulfides from organoyl iodides and elemental chalcogen catalyzed by CuO nanoparticles

In this study CuO nanoparticles were applied as a catalyst for CSe, CTe, and CS bond formation. The reaction was performed with organoyl iodides and elemental selenium, tellurium or sulfur under microwave irradiation in the presence of a base and solvent at 80 °C. This novel protocol allowed the synthesis of a variety of diselenides, ditellurides and disulfides in good to excellent yields in a very short reaction time.

Ultrasound-assisted synthesis of symmetrical biaryls by palladium-catalyzed detelluration of 1,2-diarylditellanes

An ultrasound-assisted synthesis of functionalized symmetrical biaryls with electron-withdrawing or electron-donating substituents is described and illustrated by the palladium-catalyzed detelluration of 1,2-diarylditellanes. This procedure offers easy access to symmetrical biaryls in short reaction time and the products are achieved in good to excellent yields.

An efficient one-pot synthesis of symmetrical diselenides or ditellurides from halides with CuO nanopowder/Se0 or Te0/base

(Equation Presented). A CuO nanopowder-catalyzed coupling reaction of aryl, alkyl, and heteroaryl iodides with elemental selenium and tellurium takes place in the presence of KOH at 90 °C in DMSO. A wide range of substituted symmetrical diselenides and ditellurides were afforded with good to excellent yields.

Direct Synthesis of Some Diaryl Ditellurides from Aryl Halides

The reaction of aryl halides with sodium hydrogen telluride in dimethylformamide is studied.Some diaryl ditellurides are synthesized under mild conditions by the reaction.

Improved preparation of diaryl ditellurides

Diaryl ditellurides have been synthesized from aryl bromides via lithiation, tellurium insertion, and ferricyanide oxidation of the resulting lithium arenetellurolates.