36089-71-1

Upstream product

• 5656-44-0 4-(allylthio)phenol 
• 350-46-9 4-Fluoronitrobenzene 
• 637-89-8 4-sulfanylphenol 
• 100-00-5 4-chlorobenzonitrile 

Downstream Products

• 869577-51-5 MMP₂ inhibitor II 
• 869577-53-7 {4-[4-(methanesulfonamido)phenoxy]phenylsulfonyl}methylthiirane 
• 1333379-50-2 C₂₇H₃₉N₉O₅S₂ 
• 1333379-23-9 4-[4-((thiiran-2-yl)methylsulfonyl)phenoxy]benzamine hydrochloride salt 
• 1333379-22-8 tert-butyl (4-(4-((thiiran-2-ylmethyl)sulfonyl)phenoxy)phenyl)carbamate 
• 1333379-37-5 C₅₂H₇₉N₉O₁₅S₂ 
• 1333481-67-6 ND-478 
• 1333379-36-4 C₃₆H₅₁N₅O₁₀S₂ 
• 1333379-21-7 t-butyl [4-(4-(allylthio)phenoxy)phenyl]carbamate 
• 1333481-66-5 C₂₀H₂₂N₂O₆S₂*ClH 
• 1333481-65-4 C₂₁H₂₇N₃O₄S₂*ClH 
• 1333379-35-3 C₃₁H₄₃N₃O₈S₂ 
• 1333481-64-3 C₁₇H₁₈N₂O₄S₂*ClH 
• 1333379-34-2 C₂₂H₂₆N₂O₆S₂ 

Relevant academic research and scientific papers

Selective water-soluble gelatinase inhibitor prodrugs

SB-3CT (1), a selective and potent thiirane-based gelatinase inhibitor, is effective in animal models of cancer metastasis and stroke; however, it is limited by poor aqueous solubility and extensive metabolism. We addressed these issues by blocking the pr

INHIBITORS OF MATRIX METALLOPROTEINASES

The present invention provides novel compounds of formulas I-IX, as described herein. Also provided are compositions of compounds of formulas I-IX, methods of making compounds of formulas I-IX, and methods of using compounds of formulas I-IX. The compounds of the invention can be used to inhibit matrix metalloproteinases, and are useful to treat conditions and diseases associated therewith.