361-39-7 Usage
Uses
Used in Pharmaceutical Synthesis:
2-Nitro-3,4,6-trifluoroaniline serves as a key intermediate in the production of various pharmaceuticals. Its specific molecular structure allows it to be a building block for the synthesis of drugs with targeted therapeutic effects.
Used in Agrochemical Production:
In the agrochemical industry, 2-Nitro-3,4,6-trifluoroaniline is utilized as an intermediate for the development of compounds that have applications in crop protection and pest control, contributing to the enhancement of agricultural productivity.
Used in Dye Manufacturing:
2-Nitro-3,4,6-trifluoroaniline is employed as an intermediate in the synthesis of dyes, where its chemical structure contributes to the color properties and stability of the final dye products.
Used in Fluorescent Brightener Production:
2-Nitro-3,4,6-trifluoroaniline also plays a role in the creation of fluorescent brighteners, which are used in various applications to enhance the whiteness and brightness of materials in products such as textiles, paper, and plastics.
Precaution:
It is crucial to handle 2-Nitro-3,4,6-trifluoroaniline with care due to its toxic nature. Exposure may result in skin and eye irritation, necessitating proper safety measures during its use and disposal.
Check Digit Verification of cas no
The CAS Registry Mumber 361-39-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,6 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 361-39:
(5*3)+(4*6)+(3*1)+(2*3)+(1*9)=57
57 % 10 = 7
So 361-39-7 is a valid CAS Registry Number.
361-39-7Relevant academic research and scientific papers
Di- and Trifluorinated 2-Azidobenzimidazole Derivatives: Synthesis, Photooxygenation, and 19F NMR Prediction
Kanitz, Nils E.,Fresia, Marvin,Jones, Peter G.,Lindel, Thomas
, p. 3573 - 3578 (2021/07/22)
The photoreactivity of a series of hitherto unknown, multiply fluorinated 2-azidobenzimidazole derivatives was investigated. The synthesis of the starting material includes regioselective p-defluorination of nitrobenzene derivatives employing Ogoshi's conditions. If the 6-position was unsubstituted, irradiation in the presence of N-protected amino acids at 300 nm (Rayonet) led to the formation of arylesters by oxygenation of the 6-position in good to excellent yields and perfect regioselectivity. We did not observe any displacement of fluoride. If the 6-position itself was fluorinated, alternative positions of the benzene portion were attacked. Mechanistically, the reaction proceeds through ring opening of the singlet nitrene to the cyanodiimine or via the iminobenzimidazolium ion. The availability of a set of fluorinated photo-adducts prompted the quantum chemical calculation of their 19F NMR chemical shifts. Even with the most suitable method investigated (ωB97XD/TApr-cc-pVDZ), deviations of up to 5 ppm from the experimental values were observed, underlining the importance of experimental measurements.
