36102-06-4Relevant academic research and scientific papers
Oximes as reusable templates for the synthesis of ureas and carbamates by an: In situ generation of carbamoyl oximes
Senadi, Gopal Chandru,Mutra, Mohana Reddy,Lu, Ting-Yi,Wang, Jeh-Jeng
supporting information, p. 4272 - 4277 (2017/09/28)
Oximes have been identified as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes under metal-free conditions. The recovered oxime has been utilised for three trials in the synthesis of urea derivatives without any loss in the yield and efficiency. In addition, this template approach could override the usage of hazardous and less stable isocyanates as substrates.
A New Convenient Method for the Synthesis of Symmetrical and Unsymmetrical N,N'-Disubstituted Ureas
Izdebski, Jan,Pawlak, Danuta
, p. 423 - 425 (2007/10/02)
A new method is described for the preparation of symmetrically and unsymmetrically disubstituted ureas by aminolysis of bis(4-nitrophenyl) carbonate.The second substitution is slower than the first one, and it is possible to isolate monosubstituted intermediates when equimolar amounts of substrates are used.The reaction of the intermediates with different amines give unsymmetrical derivatives of urea.
